Letters To The Editor
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World J Gastroenterol. Jul 21, 2013; 19(27): 4445-4446
Published online Jul 21, 2013. doi: 10.3748/wjg.v19.i27.4445
Word of caution before implementing ketotifen for gastrointestinal transit improvement
Kostan W Reisinger, Jacco J de Haan, Marc H Schreinemacher
Kostan W Reisinger, Jacco J de Haan, Marc H Schreinemacher, Department of Surgery, Maastricht University Medical Center and NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University, 6200 MD Maastricht, The Netherlands
Author contributions: Reisinger KW and Schreinemacher MH performed the majority of experiments; de Haan JJ was involved in setting up the study design and all authors were involved in writing and editing the manuscript.
Correspondence to: Kostan W Reisinger, MD, Department of Surgery, Maastricht University Medical Center and NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands. k.reisinger@maastrichtuniversity.nl
Telephone: +31-43-3882125 Fax: +31-43-3884154
Received: February 21, 2013
Revised: June 4, 2013
Accepted: June 8, 2013
Published online: July 21, 2013
Core Tip

Core tip: Prolonged postoperative ketotifen impairs gastrointestinal transit in a rodent ileus induction model.