Copyright
©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. May 28, 2013; 19(20): 3096-3107
Published online May 28, 2013. doi: 10.3748/wjg.v19.i20.3096
Published online May 28, 2013. doi: 10.3748/wjg.v19.i20.3096
Prediction of risk factors for lymph node metastasis in early gastric cancer
Gang Ren, Wen-Hua Li, Department of Radiology, Xinhua Hospital, Shanghai Jiaotong University Medical School, Shanghai 200092, China
Rong Cai, Ye-Ning Jin, Department of Radiochemotherapy, Ruijin Hospital, Shanghai Jiaotong University Medical School, Shanghai 200025, China
Wen-Jie Zhang, Jin-Ming Ou, Department of Surgery, Xinhua Hospital, Shanghai Jiaotong University Medical School, Shanghai 200092, China
Author contributions: Ren G and Cai R contributed equally to this paper; Ren G and Cai R performed the data acquisition, statistical analysis and interpretation; Zhang WJ, Ou JM and Jin YN performed data acquisition; Li WH designed the study and wrote the manuscript.
Supported by Shanghai Jiaotong University Medical School for Scientific Research, No. 09XJ21013; Shanghai Health Bureau for Scientific Research, No. 2010029; Shanghai Science and Technology Commission for Scientific Research, No. 124119a0300
Correspondence to: Dr. Wen-Hua Li, Department of Radiology, Xinhua Hospital, Shanghai Jiaotong University Medical School, 1665 Kongjiang Road, Shanghai 200092, China. liwhxh120819@hotmail.com
Telephone: +86-21-25078999 Fax: +86-21-65153984
Received: November 27, 2012
Revised: December 19, 2012
Accepted: March 8, 2013
Published online: May 28, 2013
Revised: December 19, 2012
Accepted: March 8, 2013
Published online: May 28, 2013
Core Tip
Core tip: Early gastric cancer (EGC) is defined as a lesion confined to the mucosa or the submucosa, irrespective of the presence of regional lymph node metastases. In this study, we retrospectively evaluated the distribution of metastatic nodes in a two-center cohort of 202 patients with EGC. To assess nodal status in EGC, we applied an index calculated by the multiplication of the incidence of metastases in the respective node stations. Univariate and multivariate analyses were applied to confirm the clinicopathological factors associated with lymph node metastases, and to provide a basis for choosing the optimal surgical treatment and for determining the appropriate range of lymph node dissection.