Published online May 21, 2013. doi: 10.3748/wjg.v19.i19.2963
Revised: February 6, 2013
Accepted: February 28, 2013
Published online: May 21, 2013
Core tip: The occurrence and development of type 2 diabetes mellitus (T2DM) is accompanied by an inflammatory response. Monocyte chemoattractant protein (MCP)-1 is a member of the CC chemokine subfamily, and is a key mediator of inflammation. MCP-1 also belongs to the chemokine superfamily. T2DM subclinical vascular lesions are a type of mild inflammation. Endothelial cell MCP-1 can be increased markedly. Danzhijiangtang capsule is a traditional Chinese medicine compound preparation. The technique can restrain mononuclear cell chemotactic activity by supplementing qi, nourishing yin and invigorating blood circulation, thereby preventing and treating subclinical vascular lesions.