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©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Dec 21, 2012; 18(47): 6935-6942
Published online Dec 21, 2012. doi: 10.3748/wjg.v18.i47.6935
Published online Dec 21, 2012. doi: 10.3748/wjg.v18.i47.6935
Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis
Kazuya Shinmura, Masanori Goto, Hong Tao, Shun Matsuura, Haruhiko Sugimura, Department of Tumor Pathology, Hamamatsu University School of Medicine, Shizuoka 431-3192, Japan
Tomonari Matsuda, Research Center for Environmental Quality Management, Kyoto University, Shiga 520-0811, Japan
Author contributions: Shinmura K conceived the study, performed the experiments, and wrote the manuscript; Goto M, Tao H and Matsuura S performed part of the experiments; Matsuda T and Sugimura H analyzed the data; all the authors were involved in the writing of the paper and approved the final version of the manuscript.
Supported by Grants from the Ministry of Health, Labour and Welfare (21-1); the Japan Society for the Promotion of Science (22590356 and 22790378); the Hamamatsu Foundation for Science and Technology Promotion, the Ministry of Education, Culture, Sports, Science and Technology (221S0001); the Takeda Science Foundation; the Aichi Cancer Research Foundation; and the Smoking Research Foundation
Correspondence to: Kazuya Shinmura, MD, PhD, Department of Tumor Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi Ward, Hamamatsu, Shizuoka 431-3192, Japan. kzshinmu@hama-med.ac.jp
Telephone: +81-53-4352220 Fax: +81-53-4352225
Received: June 20, 2012
Revised: September 19, 2012
Accepted: September 22, 2012
Published online: December 21, 2012
Revised: September 19, 2012
Accepted: September 22, 2012
Published online: December 21, 2012
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