Survival-associated alternative splicing events interact with the immune microenvironment in stomach adenocarcinoma
Zai-Sheng Ye, Miao Zheng, Qin-Ying Liu, Yi Zeng, Sheng-Hong Wei, Yi Wang, Zhi-Tao Lin, Chen Shu, Qiu-Hong Zheng, Lu-Chuan Chen
Zai-Sheng Ye, Yi Zeng, Sheng-Hong Wei, Yi Wang, Zhi-Tao Lin, Chen Shu, Lu-Chuan Chen, Department of Gastrointestinal Surgical Oncology, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, Fuzhou 350014, Fujian Province, China
Miao Zheng, Department of Clinical Laboratory, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001, Fujian Province, China
Qin-Ying Liu, Qiu-Hong Zheng, Department of Fujian Provincial Key Laboratory of Tumor Biotherapy, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, Fuzhou 350014, Fujian Province, China
Author contributions: Ye ZS designed the project, analyzed data, prepared figures, and wrote the manuscript; Chen LC conceived the study, supervised the results, critically revised/wrote the manuscript, and was responsible for its financial support and the corresponding works; all the other authors conceived the study, and critically revised the manuscript; all authors approved the final manuscript, Ye ZS, Zheng M, Zeng Y, Wei SH and Liu QY contributed equally to the work.
Supported by the National Clinical Key Specialty Construction Program of China and Grants from the National Science Foundation Project of the Fujian Science and Technology Department, No. 2017J01264 and No. 2018Y0015; the Foundation for Fujian Provincial Health Technology Project, No. 2019-ZQN-16, No. 2019-CXB-9, and No. 2019006; and the Startup Fund for Scientific Research, Fujian Medical University, No. 2017Q1219 and No. 2017Q1220.
Institutional review board statement: The manuscript used data from TCGA database, which is a common database. The Institutional review board statement was not addressed in this article.
Clinical trial registration statement: The manuscript used data from TCGA database, which is a common database. The Clinical trial registration statement was not addressed in this article.
Informed consent statement: The manuscript used data from TCGA database, which is a common database. The Informed consent statement was not addressed in this article.
Conflict-of-interest statement: The authors have declared that no competing interests exist.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
http://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Lu-Chuan Chen, BM BCh, MD, Chief Doctor, Director, Surgical Oncologist, Department of Gastrointestinal Surgical Oncology, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, No. 420 Fuma Road, Jin’an District, Fuzhou 350014, Fujian Province, China. luchuanchen@fjzlhospital.com
Received: December 24, 2020
Peer-review started: December 25, 2020
First decision: January 17, 2021
Revised: January 23, 2021
Accepted: April 9, 2021
Article in press: April 9, 2021
Published online: June 7, 2021
