Published online Jan 14, 2018. doi: 10.3748/wjg.v24.i2.211
Peer-review started: November 7, 2017
First decision: November 14, 2017
Revised: November 27, 2017
Accepted: December 5, 2017
Article in press: December 5, 2017
Published online: January 14, 2018
Post-Endoscopic submucosal dissections (ESD) bleeding is one of crucial adverse events for patients who take anti-thrombotic agents.
Although there were several reports with regard to polyglycolic acid sheet (PGAs) to prevent post-ESD bleeding, it is difficult to deliver and cover the post-ESD ulcer floor with PGAs. Developing new measurement or device to deliver PGAs is necessary to perform safer ESD.
To evaluate the efficacy of appropriate and rapid PGAs delivery method using innovative device delivery station system (DDSS).
Beagle dogs were used in this pilot basic study. Two ESDs 4 cm in diameter were performed (total 6 ESDs performed). Covering times of PGAs only by pan-endoscope, post ESD bleedings and perforations during ESD were investigated.
DDSS made it possible to cover post-ESD ulcer rapidly and reduce the post-ESD adverse event (bleeding of 1-7 d after ESD).
DDSS was very useful for rapid delivering and tight attachment of PGAs to control post-ESD bleeding. DDSS can deliver lots of endoscopic devices and surgical materials that can be placed within the digestive tract under sealed conditions.
DDSS has innovative potentials of multi-purpose device delivery measurements.
Multi-center prospective studies are needed to confirm the advantages of DDSS not only for PGAs delivery but also other endoscopic devices and materials.