Colorectal Cancer
Copyright ©The Author(s) 2003. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 15, 2003; 9(2): 288-290
Published online Feb 15, 2003. doi: 10.3748/wjg.v9.i2.288
Angiography for diagnosis and treatment of colorectal cancer
Jin Gu, Zhao-Lai Ma, Ying Li, Ming Li, Guang-Wei Xu
Jin Gu, Ming Li, Guang-Wei Xu, Department of Surgery, Oncology School of Peking University, Beijing, Beijing 100036, China
Zhao-Lai Ma, Department of Surgery, the Third Hospital of Peking University, Beijing, 100083, China
Ying Li, Department of Surgery, Beijing Chaoyang Hospital, Beijing 100044, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Jin Gu, Department of Surgery, Oncology School of Peking University, 52 FuCheng Road, Beijing 100036, China.
Telephone: +86-10-88141032 Fax: +86-10-88122437
Received: July 8, 2002
Revised: July 14, 2002
Accepted: July 27, 2002
Published online: February 15, 2003

AIM: To evaluate the role of preoperative angiography in the diagnosis and treatment of colorectal cancer.

METHODS: The authors performed selective arterial cannulation by Seldinger's method in 47 patients to locate the primary cancer and to diagnose metastasis to the liver. Each patient was then given intra-arterial regional chemotherapy, and received 5-fluorouracil (5-Fu, 1000 mg), mitomycin C (MMC, 20 mg), and cisplatinum (CDDP, 80 mg).

RESULTS: The location and shape of each tumor were observed, including metastatic tumors in the liver, in 42 of the 47 (89.4%) patients. The site of the primary tumor was difficult to identify in 5 cases because the patients had a recurrence of cancer. Arterial chemotherapy was performed successfully in all patients. The authors recorded no partial or significant morbidity resulted from angiography. The only incident was bleeding from the artery puncture site in one patient, which was successfully stopped by general medication.

CONCLUSION: Preoperative selective arterial angiography can help the diagnosis and locate primary tumors and to detect liver metastasis. At the same time, regional arterial chemotherapy can be an important form of preoperative therapy.

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