Liver Cancer
Copyright ©The Author(s) 2003. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 15, 2003; 9(10): 2194-2197
Published online Oct 15, 2003. doi: 10.3748/wjg.v9.i10.2194
Total vascular exclusion technique for resection of hepatocellular carcinoma
Zhen-Yu Yin, Xiao-Ming Wang, Ren-Xiang Yu, Bai-Meng Zhang, Ke-Ke Yu, Ning Li, Jie-Shou Li
Zhen-Yu Yin, Ning Li, Jie-Shou Li, Institute of General Surgery, School of Medicine, Nanjing University, Nanjing 210093, Jiangsu Province, China
Zhen-Yu Yin, Xiao-Ming Wang, Ren-Xiang Yu, Bai-Meng Zhang, Ke-Ke Yu, Department of General Surgery, Zhongshan Hospital, Xiamen 361004, Fujian Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Zhen-Yu Yin, Department of General Surgery, Zhongshan Hospital, Xiamen 361004, Fujian Province, China. davidmd@sohu.com
Telephone: +86-592-2292045 Fax: +86-592-2212328
Received: May 13, 2003
Revised: May 25, 2003
Accepted: June 2, 2003
Published online: October 15, 2003
Abstract

AIM: To improve the low resection rate, poor prognosis and to control the massive hemorrhage during operation, total vascular exclusion (TVE) technique was used in hepatectomies of advanced and complicated hepatocellular carcinomas (HCCs).

METHODS: Five hundred and thirty patients with HCCs were admitted in our hospital. They were divided into TVE technique group (group A: n = 78), Pringle maneuver method group (group B: n = 176) and unresectable group (group C: n = 276). The clinical, operative, pathological parameters and outcome of the patients were statistically evaluated.

RESULTS: Group A had a significantly higher resection rate than group B (accounting for 47.92% and 33.21% respectively). There was no significant difference in blood loss, blood transfusion and perioperative mortality between groups A and B. Both groups had the similar median disease free survival time (14.6 vs 16.3 months) and 1 year survival rate (92.9% vs 95.5%). The TVE group had a medial survival time of 40.5 months and its 5-year survival rate was 34.6%.

CONCLUSION: As compared with Pringle maneuver method, the total vascular exclusion is a safe and effective technique to increase the total resection rate of advanced and complicated HCCs.

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