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©The Author(s) 2003. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 15, 2003; 9(10): 2140-2142
Published online Oct 15, 2003. doi: 10.3748/wjg.v9.i10.2140
Published online Oct 15, 2003. doi: 10.3748/wjg.v9.i10.2140
Pathophysiological aspects of diverticular disease of colon and role of large bowel motility
Gabrio Bassotti, Fabio Chistolini, Antonio Morelli, Clinica di Gastroenterologia ed Epatologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Perugia, Italy
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Gabrio Bassotti, Strada del Cimitero, 2/a, 06131 San Marco (Perugia), Italy. gabassot@tin.it
Telephone: +39-75-5847570 Fax: +39-75-5847570
Received: June 16, 2003
Revised: July 7, 2003
Accepted: July 14, 2003
Published online: October 15, 2003
Revised: July 7, 2003
Accepted: July 14, 2003
Published online: October 15, 2003
Abstract
Colonic diverticular disease (diverticulosis) is one of the most common gastrointestinal disorders in Western countries. This disorder is strictly related to aging and fibre intake, and still bears a discrete amount of morbidity. Numerous etiological co-factors have to date been implicated in the pathogenesis of the disease, yet the supporting evidence is still far from absolute. The present review considers the pathophysiology of colonic diverticular disease, with a special emphasis on factors related to abnormal colonic motility.
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