Copyright ©The Author(s) 2002. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 15, 2002; 8(3): 393-399
Published online Jun 15, 2002. doi: 10.3748/wjg.v8.i3.393
Radiofrequence ablation of liver cancers
Lian-Xin Liu, Hong-Chi Jiang, Da-Xun Piao
Lian-Xin Liu, Hong-Chi Jiang, Da-Xun Piao, Department of Surgery, the First Clinical College, Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Author contributions: All authors contributed equally to the work.
Supported by Youth Natural Scientific Foundation of Heilongjiang Province; Natural Scientific Foundation of Harbin
Correspondence to: Dr. Lian-Xin Liu, Department of Surgery, the First Clinical College, Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin 150001, Heilongjiang Province, China.
Received: May 10, 2002
Revised: May 14, 2002
Accepted: May 18, 2002
Published online: June 15, 2002

Primary and secondary malignant liver cancers are some of most common malignant tumors in the world. Chemotherapy and radiotherapy are not very effective against them. Surgical resection has been considered the only potentially curtive option, but the majority of patients are not candidates for resection because of tumor size, location near major intrahepatic blood vessels and bile ducts, precluding a margin-negative resection, cirrhotic, hepatitis virus infection or multifocial. Radiofrequence ablation (RFA), which is a new evolving effective and minimally invasive technique, can produce coagulative necrosis of malignant tumors. RFA should be used percutaneously, laparscopically, or during the open laparotomy under the guidance of ultrasound, CT scan and MRI. RFA has lots of advantages superior to other local therapies including lower complications, reduced costs and hospital stays, and the possibility of repeated treatment. In general, RFA is a safe, effective treatment for unresectable malignant liver tumors less than 7.0 cm in diameter. We review the principle, mechanism, procedures and experience with RFA for treating malignant liver tumors.

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