Published online Feb 15, 1999. doi: 10.3748/wjg.v5.i1.31
Revised: November 20, 1998
Accepted: December 12, 1998
Published online: February 15, 1999
AIM: To explore the risk factors of gallbladder stone recurrence.
METHODS: A multifactorial analysis was made for 1058 patients in Shanghai area whose gall-bladder stones disappeared after different kinds of nonsurgical therapy, including oral litholytic therapy, extracorporeal shock wave lithotripsy and percutaneous choledocholithotripsy. Serum level of in sulin and total bile acid were deter-mined in 122 patients.
RESULTS: After 1-8.8 years of follow-up, the re-currence rate of gallbladder stone was 11.6%, 22.4%, 29.5%, 36.4%, 39.3% and 39.7% re-spectively within 1, 2, 3, 4, 5 and over 5 years. The risk factors for the recurrence are: primary multiple gallstones (P < 0.05); family history of cholecysto lithiasis (P < 0.05); greasy food in-take (P < 0.01); low mean value of serum insulin (P < 0.01); and high mean value of total bile acid (P < 0.01).
CONCLUSION: The recurrence of cholecys-tolithiasis is related to overintake of high fat and high cholesterol food, and might also be related to low level of serum insulin.