Sun SM, Xu JH, Sun SQ, Ma T, Wu MY, Wu LB, Chen K, Liu WX. Experimental study of chemical cholecystectomy through abdominoscopic technology. World J Gastroenterol 1998; 4(Suppl2): 38-40 [DOI: 10.3748/wjg.v4.iSuppl2.38]
Corresponding Author of This Article
Dr. Shu-Ming Sun, Associate Surgeon-in-charge of general surgery, Visiting Surgeon, Department of General Surgery, the First Affiliated Hospital, Medical College of Shantou University, Shantou 515041, Guangdong Province, China
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World J Gastroenterol. Oct 15, 1998; 4(Suppl2): 38-40 Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.38
Experimental study of chemical cholecystectomy through abdominoscopic technology
Shu-Ming Sun, Jian-Heng Xu, Shu-Qing Sun, Tao Ma, Ming-Yao Wu, Li-Biao Wu, Kui Chen, Wan-Xiu Liu
Shu-Ming Sun, Jian-Heng Xu, Tao Ma, Li-Biao Wu, Wan-Xiu Liu, Department of General Surgery, the First Affiliated Hospital, Medical College of Shantou University, Shantou 515041, Guangdong Province, China
Shu-Qing Sun, Guangdong Provincial Medical Information Institute, Guangzhou 510180, Guangdong Province, China
Ming-Yao Wu, Department of Pathology, College of Shantou University, Shantou 515041, Guangdong Province, China
Kui Chen, Department of Surgery, Medical College of Shantou University, Shantou 515041, Guangdong Province, China
Shu-Ming Sun, male, born in 1967-05-27 in Jieyang City of Guangdong Province, Han nationality, graduated from Shantou Medical College University in 1992, associate surgeon-in-charge of general surgery, visiting surgeon, having 9 papers and 1 book published.
Author contributions: All authors contributed equally to the work.
Supported by the Youth Scientific Research Foundation of Guangdong Province (199619).
Correspondence to: Dr. Shu-Ming Sun, Associate Surgeon-in-charge of general surgery, Visiting Surgeon, Department of General Surgery, the First Affiliated Hospital, Medical College of Shantou University, Shantou 515041, Guangdong Province, China
Telephone: +86-754-8258290-3256
Received: November 26, 1997 Revised: December 10, 1997 Accepted: January 6, 1998 Published online: October 15, 1998
Abstract
AIM: To verify through animal experiment the validity of chemical cholecytectomy.
METHODS: Experimental animals used were healthy juvenile pigs. A 3cm incision was made at the right costal margin for passing the cold lig ht source and some laparoscopic instruments into the abdominal cavity. The cystic duct was clamped with a siver clip and the gallbladder perfused with anhydrous alcohol (the sclerosing agent used). Gross observations and microscopic studies of the gallbladder, cystic duct, duodenum and adjoining liver specimens were made at the end of 2, 4, 6, 8, and 10 wk.
RESULTS: Coagulative necrosis and inflammatory reaction of the gallbladder and cystic duct appeared early, followed by extensive fibrosis and scar formation by the 8th week, and at the end of 10 wk complete fibrosis of the whole gallbladder occurred.
CONCLUSION: Chemical cholecystectomy is a safe, reliable, simple and practical minor surgical technique.
