Original Articles
Copyright ©The Author(s) 1998. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 15, 1998; 4(1): 33-37
Published online Feb 15, 1998. doi: 10.3748/wjg.v4.i1.33
Arterial chemoembolization for hepatocellular carcinoma
Jian Fan, Gao-Jing Ten, Shi-Cheng He, Jin-He Guo, Dong-Pei Yang, Guo-Ying Weng
Jian Fan, Gao-Jing Ten, Shi-Cheng He, Jin-He Guo, Dong-Pei Yang, Guo-Ying Weng, Department of General Surgery, First Affiliated Hospital of Nanjing Railway Medical College, Nanjing 210009, Jiangsu Province, China
Jian Fan, male, born on July 22, 1955 in Nanjing City of Jiangsu Province, and graduated from Nanjing Railway Medical College, Associated Professor and Vice Dean, specializing in the field of delivery drug system and having 12 papers published.
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Jian Fan, Department of General Surgery, First Affiliated Hospital of Nanjing Railway Medical College, 87 Dingjiaqiao Road, Nanjing 210009, Jiangsu Province, China
Telephone: +86-025-3313807
Received: April 27, 1997
Revised: September 9, 1997
Accepted: October 16, 1997
Published online: February 15, 1998
Abstract

AIM: To study the therapeutic effects of transcatheter arterial three-segment chemoembolization for hepatocellular carcinoma (HCC).

METHODS: According to the anatomy of vessels, the tumor capillary networks, muscular arterioles and feeding arteries were successively occluded using lipiodol ultra-fluid (LUF), sinobufagin microsphere (SBMs) and particles of gelatin sponge (PGS). In this series of 80 cases, therapeutic effects were evaluated in 76 cases.

RESULTS: There were 22 cases (28.9%) with partial response and 41 (53.9%) with minor response in the 76 evaluated patients. The 6-month, 1-year, 2-year and 3-year survival rates were 97.4%, 86.8%, 46.1% and 27.6% respectively.

CONCLUSION: This regimen was a rational chemoembolization method for HCC patients.

Keywords: Liver neoplasm/therapy, Lipiodol, sinobufagin microsphere, gelatin sponge, chemoembolization, therapeutic