Zaghloul M, Rehman H, Sansone S, Argyriou K, Parra-Blanco A. Endoscopic treatment of scarred polyps with a non-thermal device (Endorotor): A review of the literature. World J Gastroenterol 2024; 30(12): 1706-1713 [PMID: 38617738 DOI: 10.3748/wjg.v30.i12.1706]
Corresponding Author of This Article
Adolfo Parra-Blanco, MD, PhD, FJGESNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, street number, Nottingham NG72UH, United Kingdom. adolfo.parra-blanco@nottingham.ac.uk
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Mariam Zaghloul, Department of Hepatology, Gastroenterology and Infectious Diseases, Kafrelsheikh Universit, Kafr-Elshikh 33516, Egypt
Hameed Rehman, Stefano Sansone, Adolfo Parra-Blanco, Department of Gastroenterology Service, Nottingham City Hospital Campus, Nottingham University Hospitals NHS Trust, Nottingham NG5 1PB, United Kingdom
Konstantinos Argyriou, Department of Gastroenterology, University Hospital of Larissa, Larissa 41334, Greece
Adolfo Parra-Blanco, NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG72UH, United Kingdom
Author contributions: Zaghloul M and Parra-Blanco A designed the review; Zaghloul M reviewed the literature and wrote the manuscript; Parra-Blanco A, Sansone S, Rehman H and Argyriou K reviewed the manuscript; all authors read and approved the final manuscript.
Conflict-of-interest statement: Dr. Parra-Blanco reports other from Inter scope, during the conduct of the study; other from Lumendi and CREO medical, other from Puramatrix, outside the submitted work.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Adolfo Parra-Blanco, MD, PhD, FJGESNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, street number, Nottingham NG72UH, United Kingdom. adolfo.parra-blanco@nottingham.ac.uk
Received: November 26, 2023 Peer-review started: November 26, 2023 First decision: December 14, 2023 Revised: January 22, 2024 Accepted: March 15, 2024 Article in press: March 28, 2024 Published online: March 28, 2024
Abstract
Endoscopic resection (ER) of colorectal polyps has become a daily practice in most endoscopic units providing a colorectal cancer screening program and requires the availability of local experts and high-end endoscopic devices. ER procedures have evolved over the past few years from endoscopic mucosal resection (EMR) to more advanced techniques, such as endoscopic submucosal dissection and endo-scopic full-thickness resection. Complete resection and disease eradication are the ultimate goals of ER-based techniques, and novel devices have been developed to achieve these goals. The EndoRotor® Endoscopic Powered Resection System (Interscope Medical, Inc., Northbridge, Massachusetts, United States) is one such device. The EndoRotor is a powered resection tool for the removal of alimentary tract mucosa, including post-EMR persistent lesions with scarring, and has both CE Mark and FDA clearance. This review covers available published evidence documenting the usefulness of EndoRotor for the management of recurrent colorectal polyps.
Core Tip: Colorectal cancer (CRC) screening was initiated and implemented over the last two decades with a widespread variability in strategies and coverage in different parts of Europe even after the first appearance of the European guidelines for CRC screening. Recurrent or previously manipulated lesions are usually fibrotic with tethering to the muscularis and display the non-lifting sign, making subsequent resection challenging. The EndoRotor® Endoscopic Powered Resection System is a powered debridement device for the removal of alimentary tract mucosa, including post-endoscopic mucosal resection persistent lesions with scarring, and has both CE Mark and FDA clearance. This review covers available published evidence documenting the usefulness of EndoRotor for the management of recurrent scarred colorectal polyps.
