Published online May 21, 2020. doi: 10.3748/wjg.v26.i19.2286
Peer-review started: April 22, 2020
First decision: April 29, 2020
Revised: May 4, 2020
Accepted: May 14, 2020
Article in press: May 14, 2020
Published online: May 21, 2020
In December 2019, a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified in Wuhan, China causing coronavirus disease-2019 (COVID-19). Numerous studies have shown varying degrees of liver damage in patients infected with SARS-CoV-2. However, in previous case studies of COVID-19, the exact cause of liver injury has not been clearly elucidated, nor is there clear evidence of the interaction between liver injury and COVID-19. This study will analyze the causes of liver injury in COVID-19 and the influence of liver-related complications on the treatment and prognosis of COVID-19.
Core tip: The study analyzed the causes of liver injury in coronavirus disease-2019, including direct effect of severe acute respiratory syndrome coronavirus 2 on the liver, drug-induced liver injury, and with underlying liver diseases, and talked about the therapeutic schedule, according to different etiologies. We believed it would be benefit to manage these patients well and improve their prognosis.