Review
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 7, 2015; 21(41): 11804-11814
Published online Nov 7, 2015. doi: 10.3748/wjg.v21.i41.11804
Laparoscopic sleeve gastrectomy: More than a restrictive bariatric surgery procedure?
David Benaiges, Antonio Más-Lorenzo, Albert Goday, José M Ramon, Juan J Chillarón, Juan Pedro-Botet, Juana A Flores-Le Roux
David Benaiges, Antonio Más-Lorenzo, Albert Goday, Juan J Chillarón, Juan Pedro-Botet, Juana A Flores-Le Roux, Department of Endocrinology and Nutrition, Hospital del Mar, E-08003 Barcelona, Spain
David Benaiges, Albert Goday, Juan J Chillarón, Juan Pedro-Botet, Juana A Flores-Le Roux, Department of Medicine, Universitat Autònoma de Barcelona, E-08003 Barcelona, Spain
David Benaiges, Albert Goday, José M Ramon, Juan J Chillarón, Juan Pedro-Botet, Juana A Flores-Le Roux, Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), E-08003 Barcelona, Spain
Albert Goday, CiberOBN, Instituto de Salud Carlos III, E-28029 Madrid, Spain
José M Ramon, Department of Gastrointestinal Surgery, Hospital del Mar, E-08003 Barcelona, Spain
Author contributions: All authors contributed equally to this work.
Conflict-of-interest statement: Authors declare no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: David Benaiges, PhD, Department of Endocrinology and Nutrition, Hospital del Mar, Passeig Marítim 25-29, E-08003 Barcelona, Spain. 96002@hospitaldelmar.cat
Telephone: +34-932-483902 Fax: +34-932-483254
Received: April 28, 2015
Peer-review started: May 6, 2015
First decision: June 23, 2015
Revised: August 6, 2015
Accepted: September 30, 2015
Article in press: September 30, 2015
Published online: November 7, 2015
Abstract

Sleeve gastrectomy (SG) is a restrictive bariatric surgery technique that was first used as part of restrictive horizontal gastrectomy in the original Scopinaro type biliopancreatic diversion. Its good results as a single technique have led to a rise in its use, and it is currently the second most performed technique worldwide. SG achieves clearly better results than other restrictive techniques and is comparable in some aspects to the Roux-en-Y gastric bypass, the current gold standard in bariatric surgery. These benefits have been associated with different pathophysiologic mechanisms unrelated to weight loss such as increased gastric emptying and intestinal transit, and activation of hormonal mechanisms such as increased GLP-1 hormone and decreased ghrelin. The aim of this review was to highlight the salient aspects of SG regarding its historical evolution, pathophysiologic mechanisms, main results, clinical applications and perioperative complications.

Keywords: Bariatric surgery, Sleeve gastrectomy, Severe obesity, Dyslipidemia, Hypertension, Type 2 diabetes mellitus

Core tip: The most salient aspects of sleeve gastrectomy, a restrictive bariatric surgery technique yielding better results than other restrictive techniques that cannot simply be explained by weight loss, are reviewed.