Published online Apr 28, 2015. doi: 10.3748/wjg.v21.i16.4809
Peer-review started: October 27, 2014
First decision: December 11, 2014
Revised: January 14, 2015
Accepted: March 12, 2015
Article in press: March 12, 2015
Published online: April 28, 2015
Endoscopic ultrasound (EUS) is one of the most important modalities for the diagnosis of digestive tract diseases. EUS has been evolving ever since it was introduced. New techniques such as elastography and contrast enhancement have emerged, increasing the accuracy, sensitivity and specificity of EUS for the diagnosis of digestive tract diseases including pancreatic masses and lymphadenopathy. EUS-elastography evaluates tissue elasticity and therefore, can be used to differentiate various lesions. Contrast-enhanced EUS can distinguish benign from malignant pancreatic lesions and lymphadenopathy using the intravenous injection of contrast agents. This review discusses the principles and types of these new techniques, as well as their clinical applications and limitations.
Core tip: This article primarily focuses on emerging techniques such as elastography and contrast-enhanced endoscopic ultrasound. Principles, types and clinical applications are discussed. These emerging techniques have high accuracy, sensitivity and specificity in differential diagnosis between benign and malignant lesions.