Published online Feb 21, 2014. doi: 10.3748/wjg.v20.i7.1846
Revised: November 3, 2013
Accepted: November 18, 2013
Published online: February 21, 2014
AIM: To evaluate the applicability of AIMS65 scores in predicting outcomes of peptic ulcer bleeding.
METHODS: This was a retrospective study in a single center between January 2006 and December 2011. We enrolled 522 patients with upper gastrointestinal haemorrhage who visited the emergency room. High-risk patients were regarded as those who had re-bleeding within 30 d from the first endoscopy as well as those who died within 30 d of visiting the Emergency room. A total of 149 patients with peptic ulcer bleeding were analysed, and the AIMS65 score was used to retrospectively predict the high-risk patients.
RESULTS: A total of 149 patients with peptic ulcer bleeding were analysed. The poor outcome group comprised 28 patients [male: 23 (82.1%) vs female: 5 (10.7%)] while the good outcome group included 121 patients [male: 93 (76.9%) vs female: 28 (23.1%)]. The mean age in each group was not significantly different. The mean serum albumin levels in the poor outcome group were slightly lower than those in the good outcome group (P = 0.072). For the prediction of poor outcome, the AIMS65 score had a sensitivity of 35.5% (95%CI: 27.0-44.8) and a specificity of 82.1% (95%CI: 63.1-93.9) at a score of 0. The AIMS65 score was insufficient for predicting outcomes in peptic ulcer bleeding (area under curve = 0.571; 95%CI: 0.49-0.65).
CONCLUSION: The AIMS65 score may therefore not be suitable for predicting clinical outcomes in peptic ulcer bleeding. Low albumin levels may be a risk factor associated with high mortality in peptic ulcer bleeding.
Core tip: AIMS65 score is a novel simple score for predicting outcomes for acute upper gastrointestinal bleeding (UGIB). However, this scoring system is based on analyses of data from a mixed patient population with both variceal and non-variceal UGIB. The present study focused on the effectiveness of the AIMS65 score in predicting outcomes of peptic ulcer bleeding. This retrospective single-centre study, which included 149 patients, revealed that the AIMS65 score may not be suitable for predicting outcomes in peptic ulcer bleeding. Further, low albumin levels may be a risk factor associated with high mortality in peptic ulcer bleeding.