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World J Gastroenterol. Jun 7, 2014; 20(21): 6470-6480
Published online Jun 7, 2014. doi: 10.3748/wjg.v20.i21.6470
Selection of a TIPS stent for management of portal hypertension in liver cirrhosis: An evidence-based review
Xing-Shun Qi, Ming Bai, Zhi-Ping Yang, Dai-Ming Fan
Xing-Shun Qi, Ming Bai, Zhi-Ping Yang, Dai-Ming Fan, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China
Xing-Shun Qi, Department of Gastroenterology, No. 463 Hospital of Chinese PLA, Shenyang 110045, Liaoning Province, China
Author contributions: Qi XS designed the study, performed the literature retrieval, analyzed the data, and drafted the paper; Bai M, Yang ZP and Fan DM revised this review; all authors approved the submission.
Correspondence to: Dai-Ming Fan, MD, PhD, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xincheng District, Xi’an 710032, Shaanxi Province, China. fandaim@fmmu.edu.cn
Telephone: +86-29-84771501 Fax: +86-29-82539041
Received: October 27, 2013
Revised: January 18, 2014
Accepted: February 17, 2014
Published online: June 7, 2014
Abstract

Nowadays, transjugular intrahepatic portosystemic shunt (TIPS) has become a mainstay treatment option for the management of portal hypertension-related complications in liver cirrhosis. Accumulated evidence has shown that its indications are being gradually expanded. Notwithstanding, less attention has been paid for the selection of an appropriate stent during a TIPS procedure. Herein, we attempt to review the current evidence regarding the diameter, type, brand, and position of TIPS stents. Several following recommendations may be considered in the clinical practice: (1) a 10-mm stent may be more effective than an 8-mm stent for the management of portal hypertension, and may be superior to a 12-mm stent for the improvement of survival and shunt patency; (2) covered stents are superior to bare stents for reducing the development of shunt dysfunction; (3) if available, Viatorr stent-grafts may be recommended due to a higher rate of shunt patency; and (4) the placement of a TIPS stent in the left portal vein branch may be more reasonable for decreasing the development of hepatic encephalopathy. However, given relatively low quality of evidence, prospective well-designed studies should be warranted to further confirm these recommendations.

Keywords: Transjugular intrahepatic portosystemic shunt, Portal hypertension, Liver cirrhosis, Variceal bleeding, Hepatic encephalopathy, Shunt dysfunction

Core tip: This review suggests the following: first, a 10-mm stent may be more effective than an 8-mm or 12-mm stent for the management of portal hypertension in liver cirrhosis; second, Viatorr covered stents may be recommended for maintaining the shunt patency; finally, the placement of a transjugular intrahepatic portosystemic shunt stent in the left portal vein branch may be more reasonable for decreasing the development of hepatic encephalopathy.