Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6322
Revised: January 27, 2014
Accepted: March 4, 2014
Published online: May 28, 2014
AIM: To identify clinicopathologic factors influencing the accuracy of a high-frequency catheter probe endoscopic ultrasonography (EUS) for superficial esophageal carcinomas (SECs).
METHODS: A total of 126 patients with endoscopically suspected SEC, who underwent EUS and curative treatment at Pusan National University Hospital during 2005-2013, were enrolled. We reviewed the medical records of the 126 patients and compared EUS findings with histopathologic results according to clinicopathologic factors.
RESULTS: A total of 114 lesions in 113 patients were included in the final analysis. The EUS assessment of tumor invasion depth was accurate in 78.9% (90/114) patients. Accuracy did not differ according to histologic type, tumor differentiation, tumor location, or macroscopic shape. However, accuracy significantly decreased for tumors ≥ 3 cm in size (P = 0.002). Overestimation and underestimation of the invasion depth occurred for 11 (9.6%) and 13 lesions (11.4%), respectively. In multivariate analyses, tumor size ≥ 3 cm was the only factor significantly associated with EUS accuracy (P = 0.031), and was specifically associated with the underestimation of invasion depth.
CONCLUSION: EUS using a high-frequency catheter probe generally provides highly accurate assessments of SEC invasion depth, but its accuracy decreases for tumors ≥ 3 cm.
Core tip: Endoscopic ultrasonography (EUS) using a high-frequency catheter probe generally provides a highly accurate assessment of the invasion depth of superficial esophageal cancers (SECs). However, accuracy decreases for tumors ≥ 3 cm in size, with a tendency towards underestimation for these tumors. Therefore, caution is warranted when selecting the treatment modality for SECs ≥ 3 cm in size on the basis of pretreatment EUS staging.