Case Report
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World J Gastroenterol. Apr 14, 2014; 20(14): 4106-4109
Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.4106
Primary rectal squamous cell carcinoma treated with surgery and radiotherapy
Jun-Feng Wang, Zhen-Xing Wang, Xiao-Xiao Xu, Cui Wang, Jian-Zhong Liu
Jun-Feng Wang, Cui Wang, Jian-Zhong Liu, Department of Colorectal Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Tianjin 300060, China
Zhen-Xing Wang, Department of Gastrointestinal Medical Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Tianjin 300060, China
Xiao-Xiao Xu, Department of Hematology, Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Tianjin 300060, China
Author contributions: Wang ZX and Wang JF contributed equally to this work, and wrote the report; Wang ZX, Xu XX and Wang C collected and analyzed the patient’s clinical data; Wang ZX and Liu JZ revised the paper.
Correspondence to: Jian-Zhong Liu, MD, Department of Colorectal Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Huan-Hu-Xi Road, Hexi District, Tianjin 300060, China. liujianzhong55111@163.com
Telephone: +86-22-23359337 Fax: +86-22-23359337
Received: November 15, 2013
Revised: February 13, 2014
Accepted: March 6, 2014
Published online: April 14, 2014
Abstract

Primary squamous cell carcinoma of the rectum is a rare malignancy, and the discrete dual lesions of rectum are even rarer. There is currently no effective and satisfactory treatment for this disease. Here we report a case of an elderly female with bi-primary squamous cell carcinoma of the rectum treated with radical resection and radiotherapy. The patient is still alive 43 mo after the initial curative resection of the tumor. We suggest that surgery as the primary treatment followed by concomitant radiotherapy may be an effective protocol for elderly patients with rectal squamous cell carcinoma.

Keywords: Squamous cell carcinoma, Rectum, Primary, Surgery, Radiotherapy

Core tip: Primary squamous cell carcinoma of the rectum is a rare malignancy, and the discrete dual lesions of rectum are even rarer. Our patient is still alive after surgery as the primary treatment followed by concomitant radiotherapy. It was suggested that surgery combined with radiotherapy may be an effective treatment strategy for patients with rectal squamous cell carcinoma, especially for elderly patients who cannot tolerate chemotherapy.