Published online Mar 25, 1996. doi: 10.3748/wjg.v2.i1.34
Revised: June 16, 1995
Accepted: December 17, 1995
Published online: March 25, 1996
AIM: To increase the detection rate of early gastric cancer and the positive rate of biopsy, brilliant blue (BB) chromo-endoscopy and routine endoscopy were used to examine 54 patients with gastric cancer.
METHODS: The BB staining method and steps involved the examinee being injected intramuscularly with 20 mg of Anisodamini Hydromidum, taking oral BB solution and being examined by endoscope 40-60 min later. All of the examinees were also subjected to a routine endoscopic examination.
RESULTS: Sixteen of the total 54 patients were diagnosed with early gastric cancer; the detection rate of early cancer was 29.4%. Among those, 15 cases were discovered by BB chromo-endoscopy and only 5 cases were made by the routine endoscopy. The sensitivity of BB chromo-endoscopy was significantly higher than the routine endoscopy for early gastric cancer (P < 0.01). In addition, the BB chromo-endoscopy had a higher positive rate of biopsy than the routine endoscopy (70.4% (38/54) to 94.4% (51.54), P < 0.01)
CONCLUSION: The BB chromo-endoscopy is more useful than routine endoscopy for following-up gastric precancerous lesions.