Case Report
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World J Gastroenterol. Jan 21, 2013; 19(3): 411-414
Published online Jan 21, 2013. doi: 10.3748/wjg.v19.i3.411
Gastric ischemia after epinephrine injection in a patient with liver cirrhosis
Su Young Kim, Seung-Hee Han, Kyung Han Kim, Sang Ock Kim, Sang-Young Han, Sung-Wook Lee, Yang Hyun Baek
Su Young Kim, Seung-Hee Han, Kyung Han Kim, Sang Ock Kim, Sang-Young Han, Sung-Wook Lee, Yang Hyun Baek, Department of Internal Medicine, Dong-A University College of Medicine, Busan 602-715, South Korea
Author contributions: Kim SY and Baek YH contributed equally to this work; Han SH, Kim KH, Kim SO, Han SY and Lee SW contributed to drafting the report; Kim SY and Baek YH wrote and revised the paper; and all authors contributed to analyzing the patient’s data.
Correspondence to: Yang Hyun Baek, MD, Department of Internal Medicine, Dong-A University College of Medicine, 1, 3-ga, Dongdaeshin-dong, Seo-gu, Busan 602-715, South Korea. p100100@dau.ac.kr
Telephone: +82-51-2402983 Fax: +82-51-2402087
Received: September 13, 2012
Revised: October 15, 2012
Accepted: November 11, 2012
Published online: January 21, 2013
Abstract

Endoscopic epinephrine injection is relatively easy, quick and inexpensive. Furthermore, it has a low rate of complications, and it is widely used for the management of nonvariceal upper gastrointestinal bleeding. There have been several case reports of gastric ischemia after endoscopic injection therapy. Inadvertent intra-arterial injection may result in either spasm or thrombosis, leading to subsequent tissue ischemia or necrosis, although the stomach has a rich vascular supply and the vascular reserve of the intramural anastomosis. In addition to endoscopic injection therapy, smoking, hypertension and atherosclerosis are risk factors of gastric ischemia. We report a case of gastric ischemia after submucosal epinephrine injection in a 51-year-old woman with hypertension and liver cirrhosis.

Keywords: Hematemesis, Epinephrine, Gastric ischemia, Liver cirrhosis, Hypertension