Published online Jun 21, 2013. doi: 10.3748/wjg.v19.i23.3711
Revised: April 16, 2013
Accepted: May 16, 2013
Published online: June 21, 2013
In a recent study, Rafiei et al, reported a link between a C150T polymorphism in the human inducible nitric oxide gene and Helicobacter pylori infection as a risk factor for gastric cancer among an Iranian population. Subsequently, Abadi and Kusters published a letter to the editor questioning the validity of the study because of a supposed flaw in primer design. Here we respond to the claims of Abadi and Kusters and show that the results reported in the original article are valid.
Core tip: In a recent Letter to the Editor, Abadi and Kusters brought into question the validity of a study published by Rafiei et al. Herein we respond to the claims made by Abadi and Kusters, and show that the results reported in the article originally published by Rafiei et al, are valid.