Case Report
Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Dec 21, 2012; 18(47): 7100-7103
Published online Dec 21, 2012. doi: 10.3748/wjg.v18.i47.7100
Inflammatory myofibroblastic tumor successfully treated with chemotherapy and nonsteroidals: A case report
Yun-Lu Tao, Zhen-Jun Wang, Jia-Gang Han, Ping Wei
Yun-Lu Tao, Zhen-Jun Wang, Jia-Gang Han, Department of General Surgery, Chao Yang Hospital, Affiliated to Capital Medical University, Beijing 100020, China
Ping Wei, Department of Pathology, Chao Yang Hospital, Affiliated to Capital Medical University, Beijing 100020, China
Author contributions: Tao YL and Wang ZJ designed the case report; Tao YL wrote the paper; Wang ZJ and Han JG revised the paper; Wei P performed the pathological studies.
Correspondence to: Zhen-Jun Wang, MD, Professor of Medicine, Department of General Surgery, Chao Yang Hospital, Affiliated to Capital Medical University, No. 8 Gongti Nan Lu, Chaoyang District, Beijing 100020, China. wang3zj@sohu.com
Telephone: +86-10-85231604 Fax: +86-10-65005359
Received: September 13, 2012
Revised: October 30, 2012
Accepted: November 14, 2012
Published online: December 21, 2012
Abstract

Inflammatory myofibroblastic tumor (IMT) occurring at retroperitoneal sites has rarely been reported. We report the case of a previously well 14-year-old girl with no history of abdominal disease whose past medical history and family tumor history were unremarkable. She complained of intermittent abdominal pain for one month. An abdominal mass was found on physical examination and abdominal contrast-enhanced computed tomography (CT) showed a hypodense soft mass, the size and location of which suggested a well delineated retroperitoneal tumor surrounding the superior mesenteric vessels measuring 3.3 cm × 4.5 cm × 4.5 cm with enlarged lymph nodes. The patient underwent an exploratory laparotomy followed by biopsy and was subsequently diagnosed with retroperitoneal IMT. She was successfully treated with postoperative chemotherapy and oral diclofenac sodium. Following completion of therapy the mass was no longer palpable and no longer visible on CT scanning. The use of methotrexate and cisplatin for aggressive myofibroblastic tumors is also reviewed.

Keywords: Inflammatory myofibroblastic tumor, Retroperitoneum, Chemotherapy, Nonsteroidals, Therapy