Published online May 14, 2011. doi: 10.3748/wjg.v17.i18.2356
Revised: January 29, 2011
Accepted: February 5, 2011
Published online: May 14, 2011
Bron et al presented a retrospective study regarding the prophylactic use of antibiotics for variceal hemorrhage. Antibiotics appeared to improve the survival rate of patients without increasing clostridium difficile infection (CDI). We argue against the conclusion of the authors and consider that this result may be simply due to concurrent use of metronidazole, a therapeutic agent against CDI.