Brief Article
Copyright ©2010 Baishideng. All rights reserved
World J Gastroenterol. Jul 21, 2010; 16(27): 3402-3405
Published online Jul 21, 2010. doi: 10.3748/wjg.v16.i27.3402
Sessile serrated adenomas: Demographic, endoscopic and pathological characteristics
Suryakanth R Gurudu, Russell I Heigh, Giovanni De Petris, Evelyn G Heigh, Jonathan A Leighton, Shabana F Pasha, Isaac B Malagon, Ananya Das
Suryakanth R Gurudu, Russell I Heigh, Jonathan A Leighton, Shabana F Pasha, Isaac B Malagon, Ananya Das, Division of Gastroenterology, Mayo Clinic Arizona, Scottsdale, AZ 85259, United States
Giovanni De Petris, Department of Pathology, Mayo Clinic Arizona, AZ 85259, United States
Evelyn G Heigh, Department of Kinesiology, Arizona State University, Tempe, AZ 85287, United States
Author contributions: Gurudu SR, Heigh RI, De Petris G and Das A contributed equally to the study design, data analysis and manuscript writing; Heigh EG and Malagon IB contributed to data collection; Leighton JA and Pasha SF contributed to manuscript writing.
Correspondence to: Suryakanth R Gurudu, MD, FACG, Division of Gastroenterolog, Mayo Clinic Arizona, 13400 East Shea Blvd, Scottsdale, AZ 85259, United States.
Telephone: +1-480-3106990 Fax: +1-480-3018673
Received: February 6, 2010
Revised: April 6, 2010
Accepted: April 13, 2010
Published online: July 21, 2010

AIM: To study the demographic and endoscopic characteristics of patients with sessile serrated adenoma (SSA) in a single center.

METHODS: Patients with SSA were identified by review of the pathology database of Mayo Clinic Arizona from 2005 to 2007. A retrospective chart review was performed to extract data on demographics, polyp characteristics, presence of synchronous adenomatous polyps or cancer, polypectomy methods, and related complications.

RESULTS: One hundred and seventy-one (2.9%) of all patients undergoing colonoscopy had a total of 226 SSAs. The mean (SE) size of the SSAs was 8.1 (0.4) mm; 42% of SSAs were ≤ 5 mm, and 69% were ≤ 9 mm. Fifty-one per cent of SSAs were located in the cecum or ascending colon. Approximately half of the patients had synchronous polyps of other histological types, including hyperplastic and adenomatous polyps. Synchronous adenocarcinoma was present in seven (4%) cases. Ninety-seven percent of polyps were removed by colonoscopy.

CONCLUSION: Among patients with colon polyps, 2.9% were found to have SSAs. Most of the SSAs were located in the right side and were safely managed by colonoscopy.

Keywords: Sessile serrated polyp, Sessile serrated adenoma, Colonoscopy