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World J Gastroenterol. Jun 7, 2010; 16(21): 2604-2608
Published online Jun 7, 2010. doi: 10.3748/wjg.v16.i21.2604
Published online Jun 7, 2010. doi: 10.3748/wjg.v16.i21.2604
Serologic and laboratory markers in prediction of the disease course in inflammatory bowel disease
Marla Cindy Dubinsky, Pediatric IBD Center, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States
Author contributions: Dubinsky MC solely contributed to this paper.
Correspondence to: Dr. Marla Cindy Dubinsky, Pediatric IBD Center, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States. marla.dubinsky@cshs.org
Telephone: +1-310-4237100 Fax: +1-310-4231402
Received: November 28, 2009
Revised: January 7, 2010
Accepted: January 14, 2010
Published online: June 7, 2010
Revised: January 7, 2010
Accepted: January 14, 2010
Published online: June 7, 2010
Abstract
The search for biologic markers that can assess the natural history and perhaps predict the course of individual’s disease including response to treatments over time has become an important focus of inflammatory bowel disease research. The knowledge of an individual’s prognosis can help physicians and patients make important management decisions and aid communication on risk and benefits of disease and treatment.
Keywords: Inflammatory bowel disease, Ulcerative colitis, Crohn’s disease, Perinuclear anti-neutrophil antibody, Anti-Saccharomyces cerevisiae antibody, Pouchitis, Internal penetrating, Fibrostenosing