Jeon UB, Lee JW, Choo KS, Kim CW, Kim S, Lee TH, Jeong YJ, Kang DH. Iodized oil uptake assessment with cone-beam CT in chemoembolization of small hepatocellular carcinomas. World J Gastroenterol 2009; 15(46): 5833-5837 [PMID: 19998505 DOI: 10.3748/wjg.15.5833]
Corresponding Author of This Article
Dr. Chang Won Kim, Department of Radiology, Pusan National University Hospital, 10, 1-Ga, Ami-Dong, Seo-Gu, Pusan 602-739, South Korea. radkim@hanafos.com
Article-Type of This Article
Brief Article
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World J Gastroenterol. Dec 14, 2009; 15(46): 5833-5837 Published online Dec 14, 2009. doi: 10.3748/wjg.15.5833
Iodized oil uptake assessment with cone-beam CT in chemoembolization of small hepatocellular carcinomas
Ung Bae Jeon, Jun Woo Lee, Ki Seok Choo, Chang Won Kim, Suk Kim, Tae Hong Lee, Yeon Joo Jeong, Dae Hwan Kang
Ung Bae Jeon, Jun Woo Lee, Ki Seok Choo, Department of Radiology, Pusan National University Yangsan Hospital, Yangsan 626-770, South Korea
Chang Won Kim, Suk Kim, Tae Hong Lee, Yeon Joo Jeong, Department of Radiology, Pusan National University Hospital, Pusan 602-739, South Korea
Dae Hwan Kang, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan 626-770, South Korea
Author contributions: Jeon UB performed TACE treatments, collected and analyzed the data, and wrote the manuscript; Kim CW performed TACE treatments, designed the study, collected and analyzed the data, and was involved in editing the manuscript; Lee JW, Choo KS, Kim S, Lee TH, Jeong YJ, Kang DH participated in the design and coordination of the work.
Supported by A Grant of the Korea Healthcare technology R&D Project, Ministry for Health, Welfare & Family Affairs, Republic of Korea, A091047
Correspondence to: Dr. Chang Won Kim, Department of Radiology, Pusan National University Hospital, 10, 1-Ga, Ami-Dong, Seo-Gu, Pusan 602-739, South Korea. radkim@hanafos.com
Telephone: +82-51-2407354 Fax: +82-51-2447354
Received: April 11, 2009 Revised: October 29, 2009 Accepted: November 5, 2009 Published online: December 14, 2009
Abstract
AIM: To evaluate the utility of assessing iodized oil uptake with cone-beam computed tomography (CT) in transarterial chemoembolization (TACE) for small hepatocellular carcinoma (HCC).
METHODS: Cone-beam CT provided by a biplane flat-panel detector angiography suite was performed on eighteen patients (sixteen men and two women; 41-76 years; mean age, 58.9 years) directly after TACE for small HCC (26 nodules under 30 mm; mean diameter, 11.9 mm; range, 5-28 mm). The pre-procedural locations of the tumors were evaluated using triphasic multi-detector row helical computed tomography (MDCT). The tumor locations on MDCT and the iodized oil uptake by the tumors were analyzed on cone-beam CT and on spot image directly after the procedures.
RESULTS: All lesions on preprocedural MDCT were detected using iodized oil uptake in the lesions on cone-beam CT (sensitivity 100%, 26/26). Spot image depicted iodized oil uptake in 22 of the lesions (sensitivity 85%). The degree of iodized oil uptake was overestimated (9%, 2/22) or underestimated (14%, 3/22) on spot image in five nodules compared with that of cone-beam CT.
CONCLUSION: Cone-beam CT is a useful and convenient tool for assessing the iodized oil uptake of small hepatic tumors (< 3 cm) directly after TACE.
