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©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jul 14, 2009; 15(26): 3210-3216
Published online Jul 14, 2009. doi: 10.3748/wjg.15.3210
Published online Jul 14, 2009. doi: 10.3748/wjg.15.3210
Current management strategy of hepatocellular carcinoma
Bernardino Rampone, Beniamino Schiavone, Antonio Martino, Carmine Viviano, Giuseppe Confuorto, Department of Surgery, Pineta Grande Hospital, Castel Volturno, Caserta 81100, Italy
Author contributions: Rampone B wrote and edited the paper; the others authors participated in the preparation of the manuscript; all authors read and approved the final manuscript.
Correspondence to: Dr. Bernardino Rampone, Department of Surgery, Pineta Grande Hospital, Castel Volturno, Caserta 81100, Italy. ramponebernardino@virgilio.it
Telephone: +39-823-854266
Fax: +39-823-854266
Received: April 24, 2009
Revised: June 9, 2009
Accepted: June 16, 2009
Published online: July 14, 2009
Revised: June 9, 2009
Accepted: June 16, 2009
Published online: July 14, 2009
Abstract
Hepatocellular carcinoma (HCC) still remains a considerable challenge for surgeons. Surgery, including liver transplantation, is the most important therapeutic approach for patients with this disease. HCC is frequently diagnosed at advanced stages and has a poor prognosis with a high mortality rate even when surgical resection has been considered potentially curative. This brief report summarizes the current status of the management of this malignancy and includes a short description of new pharmacological approaches in HCC treatment.
Keywords: Hepatocellular carcinoma, Locoregional procedures, Liver transplantation, Surgical resection, Systemic treatment