Case Report
Copyright ©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jan 14, 2009; 15(2): 245-247
Published online Jan 14, 2009. doi: 10.3748/wjg.15.245
Perigastric extraskeletal Ewing’s sarcoma: A case report
Radoje B Colovic, Nikica M Grubor, Marjan T Micev, Slavko V Matic, Henry Dushan Edward Atkinson, Stojan M Latincic
Radoje B Colovic, Nikica M Grubor, Marjan T Micev, Slavko V Matic, Stojan M Latincic, Institute for Digestive Diseases, Clinical Center of Serbia, Koste Todorovica 6, Belgrade 11000, Serbia
Henry Dushan Edward Atkinson, Imperial College School of Medicine, St Mary’s Hospital, Praed Street, London W2 1NY, United Kingdom
Author contributions: The surgery and clinical care of the patient was provided by Colovic RB, Grubor NM, and Matic SV; Micev MT performed the histological and immunohistochemical analyses; The paper was written by Colovic RB, Atkinson HDE and Grubor NM; Latincic SM did the literature analysis; Grubor NM carried out all the manuscript corrections and is the corresponding author.
Correspondence to: Nikica M Grubor, MD, Assistant Professor of Surgery, Institute for Digestive Diseases, First Surgical Clinic, Clinical Center of Serbia Koste Todorovica 6, Belgrade 11000, Serbia. ngrubor@eunet.yu
Telephone: +381-11-3610715
Fax: +381-11-3615569
Received: August 4, 2008
Revised: December 8, 2008
Accepted: December 15, 2008
Published online: January 14, 2009
Abstract

Ewing’s sarcoma (ES) is a neoplasm of undifferentiated small round cells, which occurs in the bones and deep soft tissues of children and adolescents. We present a rare case of a 44-year-old woman with gastric ES presenting with epigastric pain and weight loss. Ultrasound and computed tomography scans indicated a solid/cystic mass in the pancreatic tail. At laparotomy, the tumor was found attached to the posterior surface of the stomach, completely free from the pancreas, with no lymphadenopathy or local metastases. The polynodal, partly pseudocystic, dark-red soft tumor was excised. Histopathology revealed an anaplastic small-round-cell tumor with strong membranous CD99 immunoexpression. Additionally, there was patchy immunostaining for S-100 protein, vimentin, protein gene product (PGP) 9.5 and neuron-specific enolase, and weak focal CD117 cytoplasmic immunoreactivity. The patient had no adjuvant chemotherapy; her postoperative recovery was uneventful, and she remains symptom-free, and without any sign of recurrence at 20 mo. To the best of our knowledge, this is only the third ever case of gastric ES.

Keywords: Stomach, Extraskeletal, Ewing’s sarcoma