Letters To The Editor
Copyright ©2007 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Sep 14, 2007; 13(34): 4658-4659
Published online Sep 14, 2007. doi: 10.3748/wjg.v13.i34.4658
Surveillance colonoscopy practice in Lynch syndrome in the Netherlands: A nationwide survey
Jan J Koornstra, Hans FA Vasen
Jan J Koornstra, Department of Gastroenterology and Hepatology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
Hans FA Vasen, The Netherlands Foundation for the Detection of Hereditary Tumors, Department of Gastroenterology, Leiden University Medical Centre, Leiden, The Netherlands
Author contributions: All authors contributed equally to the work.
Correspondence to: Jan J Koornstra, Department of Gastroenterology and Hepatology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands. j.j.koornstra@int.umcg.nl
Telephone: +31-50-3613354 Fax: +31-50-3619306
Received: April 17, 2007
Revised: June 23, 2007
Accepted: June 30, 2007
Published online: September 14, 2007
Abstract

Lynch syndrome, or hereditary nonpolyposis colorectal cancer (HNPCC), is the most common genetic disorder predisposing to colorectal cancer. As regular colonoscopic surveillance has been shown to reduce the incidence of colorectal cancer, this strategy is recommended worldwide. Recently, several advances in colonoscopic techniques have improved detection rates of neoplasia in Lynch syndrome. In this nationwide survey, we evaluated current surveillance colonoscopy practices for Lynch syndrome in the Netherlands and the extent to which advanced techniques have been adopted in routine clinical practice.

Keywords: Lynch syndrome, Hereditary nonpolyposis colorectal cancer, Colonoscopy, Surveillance, Chromoendoscopy