Case Report
Copyright ©2006 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Aug 28, 2006; 12(32): 5234-5236
Published online Aug 28, 2006. doi: 10.3748/wjg.v12.i32.5234
Unusual gastric and pancreatic metastatic renal cell carcinoma presentation 10 years after surgery and immunotherapy: A case report and a review of literature
Chiara Riviello, Ilaria Tanini, Greta Cipriani, Pietro Pantaleo, Carlo Nozzoli, Alberto Poma, Viligiardi Riccardo, Andrea Valeri
Chiara Riviello, Ilaria Tanini, Alberto Poma, Viligiardi Riccardo, Andrea Valeri, Second Division of General and Vascular Surgery, Careggi Hospital, Florence, Italy
Greta Cipriani, Pietro Pantaleo, Department of Internal Medicine, Oncologic Day-Hospital University of Florence, Italy
Carlo Nozzoli, Second Division of Internal Medicine, Careggi Hospital, Florence, Italy
Author contributions: All authors contributed equally to the work.
Correspondence to: Chiara Riviello, MD, Department of Surgery, Azienda Ospedaliera Universitaria Careggi, Viale GB Morgagni, 85, I-50134 Florence, Italy.
Telephone: +39-0554277111
Received: August 30, 2004
Revised: October 1, 2004
Accepted: October 6, 2004
Published online: August 28, 2006

Renal cell carcinoma (RCC) is the most common renal tumor, accounting for 2%-3% of all malignancies. Though RCC is known to spread hematogenously, isolated RCC metastasis to the stomach is a rare event. In this article, we describe the clinical course of a patient who developed a pancreatic recurrence of RCC and 1 year later a gastric recurrence of RCC treated 10 years ago with a resection and interleukin-2 (IL-2).

Accumulating evidence indicates that metastatic involvement of the pancreas and stomach should be suspected in any patient with a history of RCC who presents with gastrointestinal symptoms even 10 years after RCC resection and immunotherapy.

Keywords: Renal cell carcinoma, Stomach metastasis, Interleukin-2 treatment