Published online Dec 7, 2005. doi: 10.3748/wjg.v11.i45.7208
Revised: October 23, 2005
Accepted: October 26, 2005
Published online: December 7, 2005
AIM: To explore the effects of liniment levamisole on cellular immune functions of patients with chronic hepatitis B.
METHODS: The levels of T lymphocyte subsets and mIL-2R in peripheral blood mononuclear cells (PBMCs) were measured by biotin-streptavidin (BSA) technique in patients with chronic hepatitis B before and after the treatment with liniment levamisole.
RESULTS: After one course of treatment with liniment levamisole, the levels of CD3+, CD4+, and the ratio of CD4+/CD8+ increased as compared to those before the treatment but the level of CD8+ decreased. The total expression level of mIL-2R in PBMCs increased before and after the treatment with liniment levamisole.
CONCLUSION: Liniment levamisole may reinforce cellular immune functions of patients with chronic hepatitis B.