Brief Reports
Copyright ©2005 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2005; 11(12): 1859-1861
Published online Mar 28, 2005. doi: 10.3748/wjg.v11.i12.1859
Trial of a novel endoscopic tattooing biopsy forceps on animal model
Jian-Min Si, Lei-Min Sun, Yu-Jing Fan, Liang-Jing Wang
Jian-Min Si, Lei-Min Sun, Yu-Jing Fan, Liang-Jing Wang, Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Professor Jian-Min Si, Department of Gastroenterology, Sir Run Run Shaw Hospital, Hangzhou 310016, Zhejiang Province, China. sijm@163.net
Telephone: +86-571-86090073-2005 Fax: +86-571-86044817
Received: May 11, 2004
Revised: May 12, 2004
Accepted: August 22, 2004
Published online: March 28, 2005
Abstract

AIM: To tattoo gastric mucosa with a novel medical device which could be used to monitor and follow-up gastric mucosal lesions.

METHODS: Combining endoscopic biopsy with sclerotherapy injection, we designed a new device that could perform biopsy and injection simultaneously. We performed endoscopies on a pig by using a novel endoscope tattoo biopsy forceps for 15 mo. At the same time, we used two-step method combining sclerotherapy injection needle with endoscopic biopsy. The acuity, inflammation and duration of endoscopy were compared between two methods.

RESULTS: Compared with the old two-step method, although the inflammation induced by our new device was similar, the duration of procedure was markedly decreased and the acuity of tattooing was better than the old two-step method. All characteristics of the novel device complied with national safety guidelines. Follow-up gastroscopy after 15 mo showed the stained site with injection of 1:100 0.5 mL of India ink was still markedly visible with little inflammatory reaction.

CONCLUSION: Endoscopic tattooing biopsy forceps can be widely used in monitoring precancerous lesions. Its safety and effectiveness has been established in animals.

Keywords: Gastric mucosa; Endoscopy; Lesions