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Apr 21, 2009 (publication date) through Apr 25, 2024
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World Journal of Gastroenterology
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1007-9327
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Zeng Y, Liu G, Zhou LM. Inhibitory effect of acetylshikonin on human gastric carcinoma cell line SGC-7901 |
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| URL: | https://www.wjgnet.com/1007-9327/full/v15/i15/1816.htm |
| Number | Citing Articles |
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Hai-Bing Wang, Xiao-Qiong Ma. Activation of JNK/p38 Pathway is Responsible for α-Methyl-n-butylshikonin Induced Mitochondria-Dependent Apoptosis in SW620 Human Colorectal Cancer Cells. Asian Pacific Journal of Cancer Prevention 2014; 15(15): 6321 doi: 10.7314/APJCP.2014.15.15.6321
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| 2 |
YAO XIONG, XIU-YING MA, ZIRAN ZHANG, ZHEN-JUN SHAO, YUAN-YUAN ZHANG, LI-MING ZHOU. Apoptosis induced by β,β-dimethylacrylshikonin is associated with Bcl-2 and NF-κB in human breast carcinoma MCF-7 cells. Oncology Letters 2013; 6(6): 1789 doi: 10.3892/ol.2013.1613
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| 3 |
Zhiqin Zhang, Jie Bai, Yawen Zeng, Mengru Cai, Yu Yao, Huimin Wu, Longtai You, Xiaoxv Dong, Jian Ni. Pharmacology, toxicity and pharmacokinetics of acetylshikonin: a review. Pharmaceutical Biology 2020; 58(1): 950 doi: 10.1080/13880209.2020.1818793
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María Gómez-Serranillos Cuadrado, María Ortega Hernández-Agero, Olga Palomino Ruiz-Poveda, María Carretero Accame. Medicinal Plants. 2012; : 412 doi: 10.1201/b12527-15
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Jianqing Peng, Wen Zhou, Xinyi Xia, Xiaole Qi, Luan Sun, Min Wang, Zhenghong Wu, Zhengrong Li. Encapsulation of Acetylshikonin by Polyamidoamine Dendrimers for Preparing Prominent Nanoparticles. AAPS PharmSciTech 2014; 15(2): 425 doi: 10.1208/s12249-014-0074-2
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Katarzyna Sykłowska-Baranek, Agnieszka Pietrosiuk, Anna Gawron, Anna Kawiak, Ewa Łojkowska, Małgorzata Jeziorek, Ioanna Chinou. Enhanced production of antitumour naphthoquinones in transgenic hairy root lines of Lithospermum canescens. Plant Cell, Tissue and Organ Culture (PCTOC) 2012; 108(2): 213 doi: 10.1007/s11240-011-0032-6
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Ran Zhao, Bu Young Choi, Lixiao Wei, Mangaladoss Fredimoses, Fanxiang Yin, Xiaorong Fu, Hanyong Chen, Kangdong Liu, Joydeb Kumar Kundu, Zigang Dong, Mee‐Hyun Lee. Acetylshikonin suppressed growth of colorectal tumour tissue and cells by inhibiting the intracellular kinase, T‐lymphokine‐activated killer cell‐originated protein kinase.. British Journal of Pharmacology 2020; 177(10): 2303 doi: 10.1111/bph.14981
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| 8 |
Konstantinos N. Kontogiannopoulos, Andreana N. Assimopoulou, Konstantinos Dimas, Vassilios P. Papageorgiou. Shikonin‐loaded liposomes as a new drug delivery system: Physicochemical characterization and in vitro cytotoxicity. European Journal of Lipid Science and Technology 2011; 113(9): 1113 doi: 10.1002/ejlt.201100104
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Yun Zeng, Gang Liu, Li-Ming Zhou. Antitumor Effect and Mechanism of Acetylshikonin on Murine Sarcoma 180 Cells. 2010 4th International Conference on Bioinformatics and Biomedical Engineering 2010; : 1 doi: 10.1109/ICBBE.2010.5517623
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| 10 |
Seetharaman Rajasekar, Da Jung Park, Cheol Park, Sejin Park, Young Hoon Park, Sun Tae Kim, Yung Hyun Choi, Young Whan Choi. In vitro and in vivo anticancer effects of Lithospermum erythrorhizon extract on B16F10 murine melanoma. Journal of Ethnopharmacology 2012; 144(2): 335 doi: 10.1016/j.jep.2012.09.017
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| 11 |
Heui Min Lim, Jongsung Lee, Myeong Jin Nam, See-Hyoung Park, Jos L. Quiles. Acetylshikonin Induces Apoptosis in Human Colorectal Cancer HCT-15 and LoVo Cells via Nuclear Translocation of FOXO3 and ROS Level Elevation. Oxidative Medicine and Cellular Longevity 2021; 2021: 1 doi: 10.1155/2021/6647107
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| 12 |
Yingying Fan, Shaoju Jin, Jun He, Zhenjun Shao, Jiao Yan, Ting Feng, Hong Li. Effect of β,β-Dimethylacrylshikonin on Inhibition of Human Colorectal Cancer Cell Growth in Vitro and in Vivo. International Journal of Molecular Sciences 2012; 13(7): 9184 doi: 10.3390/ijms13079184
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| 13 |
Meng‐Di Wu, Yuan‐Ying Zhang, Shu‐Ying Yi, Bei‐Bei Sun, Jing Lan, Han‐Ming Jiang, Gang‐Ping Hao. Acetylshikonin induces autophagy‐dependent apoptosis through the key LKB1‐AMPK and PI3K/Akt‐regulated mTOR signalling pathways in HL‐60 cells. Journal of Cellular and Molecular Medicine 2022; 26(5): 1606 doi: 10.1111/jcmm.17202
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| 14 |
Shao Zhen-Jun, Zhang Yuan-Yuan, Fan Ying-Ying, Jin Shao-Ju, Yan Jiao, Zheng Xiao-Wei, Chen Jian, Xiong Yao, Zhou Li-Ming. β,β-Dimethylacrylshikonin exerts antitumor activity via Notch-1 signaling pathway in vitro and in vivo. Biochemical Pharmacology 2012; 84(4): 507 doi: 10.1016/j.bcp.2012.05.013
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| 15 |
Konstantinos N. Kontogiannopoulos, Andreana N. Assimopoulou, Sophia Hatziantoniou, Kostas Karatasos, Costas Demetzos, Vassilios P. Papageorgiou. Chimeric advanced drug delivery nano systems (chi-aDDnSs) for shikonin combining dendritic and liposomal technology. International Journal of Pharmaceutics 2012; 422(1-2): 381 doi: 10.1016/j.ijpharm.2011.09.031
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Yi‐ying Wu, Li‐hong Wan, Xiao‐wei Zheng, Zhen‐jun Shao, Jian Chen, Xia‐jing Chen, Li‐tao Liu, Wen‐juan Kuang, Xian‐shu Tan, Li‐ming Zhou. Inhibitory Effects of β,β‐Dimethylacrylshikonin on Hepatocellular Carcinoma In Vitro and In Vivo. Phytotherapy Research 2012; 26(5): 764 doi: 10.1002/ptr.3623
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| 17 |
Yi-ying Wu, Ling Zhu, Xiu-ying Ma, Zheng-jun Shao, Jian Chen, Xia-jing Chen, Li-hong Wan, Li-ming Zhou. The anti-proliferation effect of Aikete injection on hepatocellular carcinoma in vitro and in vivo. Pharmaceutical Biology 2011; 49(5): 531 doi: 10.3109/13880209.2010.524652
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| 18 |
Shuang Jiang, Haotian Wang, Yan Guo, Zhi Liu, Wu Song. Acetylshikonin inhibits the migration and invasion of A375 cells by reversing EMT process via the PI3K/Akt/mTOR pathway. Biotechnology & Biotechnological Equipment 2019; 33(1): 699 doi: 10.1080/13102818.2019.1612277
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| 19 |
Da Jeong Kim, Ji Hye Lee, Hae Ryoun Park, Young Whan Choi. Acetylshikonin inhibits growth of oral squamous cell carcinoma by inducing apoptosis. Archives of Oral Biology 2016; 70: 149 doi: 10.1016/j.archoralbio.2016.06.020
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| 20 |
Wen Zhou, Ying Peng, Shao-Shun Li. Semi-synthesis and anti-tumor activity of 5,8-O-dimethyl acylshikonin derivatives. European Journal of Medicinal Chemistry 2010; 45(12): 6005 doi: 10.1016/j.ejmech.2010.09.068
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| 21 |
Ya‐Jiao Yuan, Shanshan Liu, Hong Yang, Jian‐Ling Xu, Jing Zhai, Han‐Ming Jiang, Beibei Sun. Acetylshikonin induces apoptosis through the endoplasmic reticulum stress‐activated PERK/eIF2α/CHOP axis in oesophageal squamous cell carcinoma. Journal of Cellular and Molecular Medicine 2024; 28(1) doi: 10.1111/jcmm.18030
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| 22 |
E. D. Spyrelli, A. V. Kyriazou, C. Virgiliou, A. Nakas, O. Deda, V. P. Papageorgiou, A. N. Assimopoulou, H. G. Gika. Metabolic profiling study of shikonin's cytotoxic activity in the Huh7 human hepatoma cell line. Molecular BioSystems 2017; 13(5): 841 doi: 10.1039/C6MB00830E
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| 23 |
Morteza Eskandani, Hossein Nazemiyeh. Self-reporter shikonin-Act-loaded solid lipid nanoparticle: Formulation, physicochemical characterization and geno/cytotoxicity evaluation. European Journal of Pharmaceutical Sciences 2014; 59: 49 doi: 10.1016/j.ejps.2014.04.009
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Gangping Hao, Jing Zhai, Hanming Jiang, Yuanying Zhang, Mengdi Wu, Yuyu Qiu, Cundong Fan, Lijuan Yu, Suyun Bai, Lingyun Sun, Zhongfa Yang. Acetylshikonin induces apoptosis of human leukemia cell line K562 by inducing S phase cell cycle arrest, modulating ROS accumulation, depleting Bcr-Abl and blocking NF-κB signaling. Biomedicine & Pharmacotherapy 2020; 122: 109677 doi: 10.1016/j.biopha.2019.109677
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I. Tanis, K. Karatasos, A. N. Assimopoulou, V. P. Papageorgiou. Modeling of hyperbranched polyesters as hosts for the multifunctional bioactive agent shikonin. Physical Chemistry Chemical Physics 2011; 13(22): 10808 doi: 10.1039/c1cp20271e
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| 26 |
Junbiao Wang, Romilde Iannarelli, Stefania Pucciarelli, Emiliano Laudadio, Roberta Galeazzi, Mara Giangrossi, Maurizio Falconi, Lishan Cui, Aleix Marti Navia, Michela Buccioni, Gabriella Marucci, Daniele Tomassoni, Laura Serini, Stefania Sut, Filippo Maggi, Stefano Dall’Acqua, Cristina Marchini, Augusto Amici. Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice. Pharmacological Research 2020; 161: 105123 doi: 10.1016/j.phrs.2020.105123
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| 27 |
Seok-Cheol Cho, Bu Young Choi. Acetylshikonin Inhibits Human Pancreatic PANC-1 Cancer Cell Proliferation by Suppressing the NF-κB Activity. Biomolecules & Therapeutics 2015; 23(5): 428 doi: 10.4062/biomolther.2015.102
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