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Cited by in CrossRef
For: Lim JY, Yoon SO, Seol SY, Hong SW, Kim JW, Choi SH, Cho JY. Overexpression of the M2 isoform of pyruvate kinase is an adverse prognostic factor for signet ring cell gastric cancer. World J Gastroenterol 2012; 18(30): 4037-4043 [PMID: 22912555 DOI: 10.3748/wjg.v18.i30.4037]
URL: https://www.wjgnet.com/1007-9327/full/v18/i30/4037.htm
Number Citing Articles
1
Ze Zhang, Xinyue Deng, Yuanda Liu, Yahui Liu, Liankun Sun, Fangfang Chen. PKM2, function and expression and regulationCell & Bioscience 2019; 9(1) doi: 10.1186/s13578-019-0317-8
2
Zhiyan LI, Baiwei ZHAO, Deyao ZHANG, Juan DENG, Yongming CHEN, Jian ZHOU. Diallyl disulfide regulates proliferation, apoptosis and aerobic glycolysis by down-regulating PKM2 in gastric cancer cellsMinerva Biotechnology and Biomolecular Research 2021; 33(3) doi: 10.23736/S2724-542X.20.02634-8
3
Ning Li, Dandan Meng, Yue Xu, Ling Gao, Fengqian Shen, Xiaojing Tie, Yan Zhang, Zhenying Yi, Wenjie Shen, Zonglan Liu, Zhiqiao Xu, Paula I. Moreira. Pyruvate Kinase M2 Knockdown Suppresses Migration, Invasion, and Epithelial-Mesenchymal Transition of Gastric Carcinoma via Hypoxia-Inducible Factor Alpha/B-Cell Lymphoma 6 PathwayBioMed Research International 2020; 2020: 1 doi: 10.1155/2020/7467104
4
Qing Liu, Meng Liang, Tao Liu, Lucine Vuitton, Shutao Zheng, Xiangpeng Gao, Mang Lu, Xiuling Li, Ilyar Sheyhidin, Xiaomei Lu. M2 isoform of pyruvate kinase (PKM2) is upregulated in Kazakh’s ESCC and promotes proliferation and migration of ESCC cellsTumor Biology 2016; 37(2): 2665 doi: 10.1007/s13277-015-4073-z
5
Zhu Wang, Jianhua Yin, Mingxing Li, Jing Shen, Zhangang Xiao, Yueshui Zhao, Chengliang Huang, Hanyu Zhang, Zhuo Zhang, Chi Hin Cho, Xu Wu. Combination of shikonin with paclitaxel overcomes multidrug resistance in human ovarian carcinoma cells in a P-gp-independent manner through enhanced ROS generationChinese Medicine 2019; 14(1) doi: 10.1186/s13020-019-0231-3
6
Goran Hamid Mohammad, S. W. M. Olde Damink, Massimo Malago, Dipok Kumar Dhar, Stephen P. Pereira, Michael Muders. Pyruvate Kinase M2 and Lactate Dehydrogenase A Are Overexpressed in Pancreatic Cancer and Correlate with Poor OutcomePLOS ONE 2016; 11(3): e0151635 doi: 10.1371/journal.pone.0151635
7
Wei-Ren Liu, Meng-Xin Tian, Liu-Xiao Yang, Yu-Li Lin, Lei Jin, Zhen-Bin Ding, Ying-Hao Shen, Yuan-Fei Peng, Dong-Mei Gao, Jian Zhou, Shuang-Jian Qiu, Zhi Dai, Rui He, Jia Fan, Ying-Hong Shi. PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinomaOncotarget 2015; 6(2): 846 doi: 10.18632/oncotarget.2749
8
Lian-Wen Yuan, Hiroharu Yamashita, Yasuyuki Seto. Glucose metabolism in gastric cancer: The cutting-edgeWorld Journal of Gastroenterology 2016; 22(6): 2046-2059 doi: 10.3748/wjg.v22.i6.2046
9
Haiyan Zhu, Hui Luo, Xuejie Zhu, Xiaoli Hu, Lihong Zheng, Xueqiong Zhu. Pyruvate kinase M2 (PKM2) expression correlates with prognosis in solid cancers: a meta-analysisOncotarget 2017; 8(1): 1628 doi: 10.18632/oncotarget.13703
10
Taro Sugiyama, Kohei Taniguchi, Nobuhisa Matsuhashi, Toshihiro Tajirika, Manabu Futamura, Tomoaki Takai, Yukihiro Akao, Kazuhiro Yoshida. MiR‐133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle‐splicer polypyrimidine tract‐binding protein 1Cancer Science 2016; 107(12): 1767 doi: 10.1111/cas.13091
11
Tai-Kuang Chao, Tien-Shuo Huang, Yu-Ping Liao, Rui-Lan Huang, Po-Hsuan Su, Hueng-Yuan Shen, Hung-Cheng Lai, Yu-Chi Wang, Pankaj K. Singh. Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancerPLOS ONE 2017; 12(7): e0182166 doi: 10.1371/journal.pone.0182166
12
Q-X Huang, J-Y Cui, H Ma, X-M Jia, F-L Huang, L-X Jiang. Screening of potential biomarkers for cholangiocarcinoma by integrated analysis of microarray data setsCancer Gene Therapy 2016; 23(2-3): 48 doi: 10.1038/cgt.2015.66
13
David C. Montrose, Lorenzo Galluzzi. Cellular Nutrient Utilization and CancerInternational Review of Cell and Molecular Biology 2019; 347: 1 doi: 10.1016/bs.ircmb.2019.07.007
14
Xiao‐Ling Yan, Xue‐Bin Zhang, Ran Ao, Lin Guan. Retracted : Effects of shRNA‐Mediated Silencing of PKM2 Gene on Aerobic Glycolysis, Cell Migration, Cell Invasion, and Apoptosis in Colorectal Cancer Cells Journal of Cellular Biochemistry 2017; 118(12): 4792 doi: 10.1002/jcb.26148
15
Elisabet Hjerpe, Suzanne Egyhazi Brage, Joseph Carlson, Marianne Frostvik Stolt, Kjell Schedvins, Hemming Johansson, Maria Shoshan, Elisabeth Åvall-Lundqvist. Metabolic markers GAPDH, PKM2, ATP5B and BEC-index in advanced serous ovarian cancerBMC Clinical Pathology 2013; 13(1) doi: 10.1186/1472-6890-13-30
16
JIAN CHEN, DI SUN, HONGJIN CHU, ZHAOHUA GONG, CHENGLIN ZHANG, BENJIAO GONG, YAN LI, NING LI, LIXIN JIANG. Screening of differential microRNA expression in gastric signet ring cell carcinoma and gastric adenocarcinoma and target gene predictionOncology Reports 2015; 33(6): 2963 doi: 10.3892/or.2015.3935
17
Hong Jae Chon, Chan Kim, Arthur Cho, Yoo Min Kim, Su Jin Jang, Bo Ok Kim, Chan Hyuk Park, Woo Jin Hyung, Joong Bae Ahn, Sung Hoon Noh, Mijin Yun, Sun Young Rha. The clinical implications of FDG-PET/CT differ according to histology in advanced gastric cancerGastric Cancer 2019; 22(1): 113 doi: 10.1007/s10120-018-0847-5
18
Wenjuan Li, Joan Liu, Kasey Jackson, Runhua Shi, Yunfeng Zhao, Junming Yue. Sensitizing the Therapeutic Efficacy of Taxol with Shikonin in Human Breast Cancer CellsPLoS ONE 2014; 9(4): e94079 doi: 10.1371/journal.pone.0094079
19
Carmen Chak-Lui Wong, Sandy Leung-Kuen Au, Aki Pui-Wah Tse, Iris Ming-Jing Xu, Robin Kit-Ho Lai, David Kung-Chun Chiu, Larry Lai Wei, Dorothy Ngo-Yin Fan, Felice Ho-Ching Tsang, Regina Cheuk-Lam Lo, Chun-Ming Wong, Irene Oi-Lin Ng, Pankaj K. Singh. Switching of Pyruvate Kinase Isoform L to M2 Promotes Metabolic Reprogramming in HepatocarcinogenesisPLoS ONE 2014; 9(12): e115036 doi: 10.1371/journal.pone.0115036
20
Peng Yang, Guo-Bin Ding, Wen Liu, Rong Fu, Amin Sajid, Zhuoyu Li. Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferationFood & Function 2018; 9(11): 5547 doi: 10.1039/C8FO01161C
21
Natalie A. Lockney, Manchao Zhang, Yanzhen Lu, Sabrina C. Sopha, M. Kay Washington, Nipun Merchant, Zhiguo Zhao, Yu Shyr, A. Bapsi Chakravarthy, Fen Xia. Pyruvate Kinase Muscle Isoenzyme 2 (PKM2) Expression Is Associated with Overall Survival in Pancreatic Ductal AdenocarcinomaJournal of Gastrointestinal Cancer 2015; 46(4): 390 doi: 10.1007/s12029-015-9764-6
22
Nicholas Wong, Judy Yan, Diane Ojo, Jason De Melo, Jean-Claude Cutz, Damu Tang. Changes in PKM2 Associate with Prostate Cancer ProgressionCancer Investigation 2014; 32(7): 330 doi: 10.3109/07357907.2014.919306
23
Wen Hu, Shi-Xun Lu, Min Li, Chao Zhang, Li-Li Liu, Jia Fu, Jie-Tian Jin, Rong-Zhen Luo, Chris Zhiyi Zhang, Jing-Ping Yun. Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinomaOncotarget 2015; 6(9): 6570 doi: 10.18632/oncotarget.3262
24
Tieying Dong, Xinmei Kang, Zhaoliang Liu, Shu Zhao, Wenjie Ma, Qijia Xuan, Hang Liu, Zhipeng Wang, Qingyuan Zhang. Altered glycometabolism affects both clinical features and prognosis of triple-negative and neoadjuvant chemotherapy-treated breast cancerTumor Biology 2016; 37(6): 8159 doi: 10.1007/s13277-015-4729-8
25
Caihong Wang, Shaosen Zhang, Jie Liu, Yang Tian, Boyuan Ma, Siran Xu, Yan Fu, Yongzhang Luo. Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling PathwayCell Reports 2020; 30(6): 1780 doi: 10.1016/j.celrep.2020.01.037
26
Y-C Yang, T-Y Cheng, S-M Huang, C-Y Su, P-W Yang, J-M Lee, C-K Chen, M Hsiao, K-T Hua, M-L Kuo. Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90–EGFR associationOncogene 2016; 35(26): 3387 doi: 10.1038/onc.2015.397
27
Kazuto Harada, Carol C. Wu, Xuemei Wang, Dilsa Mizrak Kaya, Fatemeh G. Amlashi, Masaaki Iwatsuki, Mariela A. Blum Murphy, Dipen M. Maru, Brian Weston, Jeffrey H. Lee, Jane E. Rogers, Irene Thomas, Namita Shanbhag, Manoop S. Bhutani, Wayne L. Hofstetter, Quynh-Nhu Nguyen, Jaffer A. Ajani. Total Lesion Glycolysis Assessment Identifies a Patient Fraction With a High Cure Rate Among Esophageal Adenocarcinoma Patients Treated With Definitive ChemoradiationAnnals of Surgery 2020; 272(2): 311 doi: 10.1097/SLA.0000000000003228
28
Atul Kumar, Mamta Singh, Dolly Sharma, Vinit Kumar, Reshma Rani. Burger's Medicinal Chemistry and Drug Discovery2021; : 1 doi: 10.1002/0471266949.bmc286
29
Tara TeSlaa, Michael A. Teitell. Conceptual Background and Bioenergetic/Mitochondrial Aspects of OncometabolismMethods in Enzymology 2014; 542: 91 doi: 10.1016/B978-0-12-416618-9.00005-4
30
Takeharu Shiroki, Misa Yokoyama, Nobuhiro Tanuma, Ryuhei Maejima, Keiichi Tamai, Kazunori Yamaguchi, Tomoyuki Oikawa, Tetsuya Noguchi, Koh Miura, Tsuneaki Fujiya, Hiroshi Shima, Ikuro Sato, Naoko Murata-Kamiya, Masanori Hatakeyama, Katsunori Iijima, Tooru Shimosegawa, Kennichi Satoh. Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolismCancer Science 2017; 108(5): 931 doi: 10.1111/cas.13211
31
YONGHUA SHEN, MIN CHEN, SHULING HUANG, XIAOPING ZOU. Pantoprazole inhibits human gastric adenocarcinoma SGC-7901 cells by downregulating the expression of pyruvate kinase M2Oncology Letters 2016; 11(1): 717 doi: 10.3892/ol.2015.3912
32
HISATAKA OGAWA, HIROAKI NAGANO, MASAMITSU KONNO, HIDETOSHI EGUCHI, JUN KOSEKI, KOICHI KAWAMOTO, NAOHIRO NISHIDA, HUGH COLVIN, AKIRA TOMOKUNI, YOSHITO TOMIMARU, NAOKI HAMA, HIROSHI WADA, SHIGERU MARUBASHI, SHOGO KOBAYASHI, MASAKI MORI, YUICHIRO DOKI, HIDESHI ISHII. The combination of the expression of hexokinase 2 and pyruvate kinase M2 is a prognostic marker in patients with pancreatic cancerMolecular and Clinical Oncology 2015; 3(3): 563 doi: 10.3892/mco.2015.490
33
Kohei Taniguchi, Yuko Ito, Nobuhiko Sugito, Minami Kumazaki, Haruka Shinohara, Nami Yamada, Yoshihito Nakagawa, Tarou Sugiyama, Manabu Futamura, Yoshinori Otsuki, Kazuhiro Yoshida, Kazuhisa Uchiyama, Yukihiro Akao. Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoformsScientific Reports 2015; 5(1) doi: 10.1038/srep08647
34
Chao Wang, Jinling Jiang, Jun Ji, Qu Cai, Xuehua Chen, Yingyan Yu, Zhenggang Zhu, Jun Zhang. PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancerScientific Reports 2017; 7(1) doi: 10.1038/s41598-017-03031-1
35
Kohei Taniguchi, Nobuhiko Sugito, Minami Kumazaki, Haruka Shinohara, Nami Yamada, Nobuhisa Matsuhashi, Manabu Futamura, Yuko Ito, Yoshinori Otsuki, Kazuhiro Yoshida, Kazuhisa Uchiyama, Yukihiro Akao. Positive feedback of DDX6/c-Myc/PTB1 regulated by miR-124 contributes to maintenance of the Warburg effect in colon cancer cellsBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2015; 1852(9): 1971 doi: 10.1016/j.bbadis.2015.06.022
36
HIROSHI SAWAYAMA, TAKATSUGU ISHIMOTO, HIDETAKA SUGIHARA, NOBUTOMO MIYANARI, YUJI MIYAMOTO, YOSHIFUMI BABA, NAOYA YOSHIDA, HIDEO BABA. Clinical impact of the Warburg effect in gastrointestinal cancer (Review)International Journal of Oncology 2014; 45(4): 1345 doi: 10.3892/ijo.2014.2563
37
Giuseppe Biamonti, Lucia Maita, Alessandra Montecucco. The Krebs Cycle Connection: Reciprocal Influence Between Alternative Splicing Programs and Cell MetabolismFrontiers in Oncology 2018; 8 doi: 10.3389/fonc.2018.00408
38
Nan Li, Lin Feng, Hui Liu, Jiadong Wang, Moses Kasembeli, My Kim Tran, David J. Tweardy, Steven Hsesheng Lin, Junjie Chen. PARP Inhibition Suppresses Growth of EGFR-Mutant Cancers by Targeting Nuclear PKM2Cell Reports 2016; 15(4): 843 doi: 10.1016/j.celrep.2016.03.070
39
Ze Qian, Wendi Hu, Zhen Lv, Hua Liu, Diyu Chen, Yacong Wang, Jian Wu, Shusen Zheng. PKM2 upregulation promotes malignancy and indicates poor prognosis for intrahepatic cholangiocarcinomaClinics and Research in Hepatology and Gastroenterology 2020; 44(2): 162 doi: 10.1016/j.clinre.2019.06.008
40
Le-Yi Wang, Yun-Peng Liu, Li-Gang Chen, Yan-Ling Chen, Li Tan, Jing-Jing Liu, Amarsanaa Jazag, Jian-Lin Ren, Bayasi Guleng, Hiromu Suzuki. Pyruvate Kinase M2 Plays a Dual Role on Regulation of the EGF/EGFR Signaling via E-Cadherin-Dependent Manner in Gastric Cancer CellsPLoS ONE 2013; 8(6): e67542 doi: 10.1371/journal.pone.0067542
41
Akiko Suzuki, Sachin Puri, Pamela Leland, Ankit Puri, Tarsem Moudgil, Bernard A. Fox, Raj K. Puri, Bharat H. Joshi, Aamir Ahmad. Subcellular compartmentalization of PKM2 identifies anti-PKM2 therapy response in vitro and in vivo mouse model of human non-small-cell lung cancerPLOS ONE 2019; 14(5): e0217131 doi: 10.1371/journal.pone.0217131
42
Nicholas Wong, Jason De Melo, Damu Tang. PKM2, a Central Point of Regulation in Cancer MetabolismInternational Journal of Cell Biology 2013; 2013: 1 doi: 10.1155/2013/242513
43
Haili Wu, Peng Yang, Wanglai Hu, Yingying Wang, Yangxu Lu, Lichao Zhang, Yongsheng Fan, Hong Xiao, Zhuoyu Li. Overexpression of PKM2 promotes mitochondrial fusion through attenuated p53 stabilityOncotarget 2016; 7(47): 78069 doi: 10.18632/oncotarget.12942
44
Annamaria Ruzzo, Francesco Graziano, Irene Bagaloni, Maria Di Bartolomeo, Michele Prisciandaro, Giuseppe Aprile, Elena Ongaro, Bruno Vincenzi, Giuseppe Perrone, Daniele Santini, Lorenzo Fornaro, Caterina Vivaldi, Gianluca Tomasello, Fotios Loupakis, Sara Lonardi, Matteo Fassan, Michele Valmasoni, Donatella Sarti, Paola Lorenzini, Vincenzo Catalano, Renato Bisonni, Michela Del Prete, Guido Collina, Mauro Magnani. Glycolytic competence in gastric adenocarcinomas negatively impacts survival outcomes of patients treated with salvage paclitaxel-ramucirumabGastric Cancer 2020; 23(6): 1064 doi: 10.1007/s10120-020-01078-0
45
Ming-Chuan Hsu, Wen-Chun Hung. Pyruvate kinase M2 fuels multiple aspects of cancer cells: from cellular metabolism, transcriptional regulation to extracellular signalingMolecular Cancer 2018; 17(1) doi: 10.1186/s12943-018-0791-3
46
Cheng Zhan, Li Yan, Lin Wang, Jun Ma, Wei Jiang, Yongxing Zhang, Yu Shi, Qun Wang, Carol J Wilusz. Isoform Switch of Pyruvate Kinase M1 Indeed Occurs but Not to Pyruvate Kinase M2 in Human TumorigenesisPLOS ONE 2015; 10(3): e0118663 doi: 10.1371/journal.pone.0118663
47
Pyruvate Kinase M2 Expression: A Potential Metabolic Biomarker to Differentiate Endometrial Precancer and Cancer That Is Associated with Poor Outcomes in Endometrial CarcinomaInternational Journal of Environmental Research and Public Health 2019; 16(23): 4589 doi: 10.3390/ijerph16234589
48
Shruti Desai, Minming Ding, Bin Wang, Zhimin Lu, Qi Zhao, Kenna Shaw, W.K. Alfred Yung, John N. Weinstein, Ming Tan, Jun Yao. Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancersOncotarget 2014; 5(18): 8202 doi: 10.18632/oncotarget.1159
49
Nicholas Wong, Diane Ojo, Judy Yan, Damu Tang. PKM2 contributes to cancer metabolismCancer Letters 2015; 356(2): 184 doi: 10.1016/j.canlet.2014.01.031
50
Guofeng Yue, Xia Sun, Ana Gimenez-Capitan, Jie Shen, Lixia Yu, Cristina Teixido, Wenxian Guan, Rafael Rosell, Baorui Liu, Jia Wei. TAZIs Highly Expressed in Gastric Signet Ring Cell CarcinomaBioMed Research International 2014; 2014: 1 doi: 10.1155/2014/393064
51
Shuichi Fukuda, Hiroshi Miyata, Yasuhiro Miyazaki, Tomoki Makino, Tsuyoshi Takahashi, Yukinori Kurokawa, Makoto Yamasaki, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki. Pyruvate Kinase M2 Modulates Esophageal Squamous Cell Carcinoma Chemotherapy Response by Regulating the Pentose Phosphate PathwayAnnals of Surgical Oncology 2015; 22(S3): 1461 doi: 10.1245/s10434-015-4522-3
52
Hitoshi Tsugawa, Hidekazu Suzuki. Gastric Cancer2019; : 51 doi: 10.1007/978-981-13-1120-8_4
53
Min Yu, Shengying Chen, Weifeng Hong, Yujun Gu, Bowen Huang, Ye Lin, Yu Zhou, Haosheng Jin, Yanying Deng, Lei Tu, Baohua Hou, Zhixiang Jian. Prognostic role of glycolysis for cancer outcome: evidence from 86 studiesJournal of Cancer Research and Clinical Oncology 2019; 145(4): 967 doi: 10.1007/s00432-019-02847-w
54
Melissa M. Grant. Pyruvate Kinase, Inflammation and Periodontal DiseasePathogens 2021; 10(7): 784 doi: 10.3390/pathogens10070784