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Number Cited Articles
1
Alfred P. See, James E. Han, Jillian Phallen, Zev Binder, Gary Gallia, Fan Pan, Dilini Jinasena, Christopher Jackson, Zineb Belcaid, Sung Jin Jeong, Chelsea Gottschalk, Jing Zeng, Jacob Ruzevick, Sarah Nicholas, Young Kim, Emilia Albesiano, Drew M. Pardoll, Michael Lim. The role of STAT3 activation in modulating the immune microenvironment of GBMJournal of Neuro-Oncology 2012; 110(3): 359 doi: 10.1007/s11060-012-0981-6
2
Ujjal Das, Sushobhan Biswas, Sreya Chattopadhyay, Anindita Chakraborty, Rakhi Dey Sharma, Asoke Banerji, Sanjit Dey. Radiosensitizing effect of ellagic acid on growth of Hepatocellular carcinoma cells: an in vitro studyScientific Reports 2017; 7(1) doi: 10.1038/s41598-017-14211-4
3
Roozbeh Dehghannasiri, Byung-Jun Yoon, Edward R Dougherty. Efficient experimental design for uncertainty reduction in gene regulatory networksBMC Bioinformatics 2015; 16(S13) doi: 10.1186/1471-2105-16-S13-S2
4
Saisai Wang, Yong Shen, Runfeng Qiu, Zhiliang Chen, Zhehang Chen, Wenbin Chen. 18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migrationInternational Journal of Oncology 2017; 51(2): 615 doi: 10.3892/ijo.2017.4059
5
Huiping Zhou, Yang Sun, Hongnan Zheng, Lei Fan, Qibing Mei, Yuan Tang, Xiaoqun Duan, Yuhua Li. Paris saponin VII extracted from trillium tschonoskii suppresses proliferation and induces apoptosis of human colorectal cancer cellsJournal of Ethnopharmacology 2019; 239: 111903 doi: 10.1016/j.jep.2019.111903
6
Junjie Zhao, Jarod Zepp, Katarzyna Bulek, Xiaoxia Li. SIGIRR, a negative regulator of colon tumorigenesisDrug Discovery Today: Disease Mechanisms 2011; 8(3-4): e63 doi: 10.1016/j.ddmec.2012.02.003
7
Bharat B Aggarwal, Prashasnika Gehlot. Inflammation and cancer: how friendly is the relationship for cancer patients?Current Opinion in Pharmacology 2009; 9(4): 351 doi: 10.1016/j.coph.2009.06.020
8
XIRUI WANG, LEI CAO, YINGYI WANG, XIEFENG WANG, NING LIU, YONGPING YOU. Regulation of let-7 and its target oncogenes (Review)Oncology Letters 2012; 3(5): 955 doi: 10.3892/ol.2012.609
9
Ben Zhao, Lu Wang, Hong Qiu, Mingsheng Zhang, Li Sun, Ping Peng, Qianqian Yu, Xianglin Yuan. Mechanisms of resistance to anti-EGFR therapy in colorectal cancerOncotarget 2017; 8(3): 3980 doi: 10.18632/oncotarget.14012
10
N.G. Shah, T.I. Trivedi, R.A. Tankshali, J.A. Goswami, D.H. Jetly, T.P. Kobawala, S.N. Shukla, P.M. Shah, R.J. Verma. Stat3 Expression in Oral Squamous Cell Carcinoma: Association with Clinicopathological Parameters and SurvivalThe International Journal of Biological Markers 2006; 21(3): 175 doi: 10.1177/172460080602100307
11
Hua Xiong, Zhi-Gang Zhang, Xiao-Qing Tian, Dan-Feng Sun, Qin-Chuan Liang, Yan-Jie Zhang, Rong Lu, Ying-Xuan Chen, Jing-Yuan Fang. Inhibition of JAK1, 2/STAT3 Signaling Induces Apoptosis, Cell Cycle Arrest, and Reduces Tumor Cell Invasion in Colorectal Cancer CellsNeoplasia 2008; 10(3): 287 doi: 10.1593/neo.07971
12
Bharat Aggarwal, Chitra Sundaram, Sahdeo Prasad, Simone Reuter, Ramaswamy Kannappan, Vivek Yadav, Byoungduck Park, Ji Kim, Subash Gupta, Kanokkarn Phromnoi, Bokyung Sung. Inflammation, Lifestyle and Chronic DiseasesOxidative Stress and Disease 2011; 20115234 doi: 10.1201/b11014-15
13
Azhar Rasul, Muhammad Khan, Muhammad Ali, Jiang Li, Xiaomeng Li. Targeting Apoptosis Pathways in Cancer with Alantolactone and IsoalantolactoneThe Scientific World Journal 2013; 2013: 1 doi: 10.1155/2013/248532
14
Chiara Rosso, Luca Cabianca, Fabrizio M. Gili. Non-invasive markers to detect colorectal cancer in asymptomatic populationMinerva Biotecnologica 2019; 31(1) doi: 10.23736/S1120-4826.18.02493-X
15
Beata Pajak, Barbara Gajkowska, Arkadiusz Orzechowski. Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells.Folia Histochemica et Cytobiologica 2008; 46(2) doi: 10.2478/v10042-008-0019-2
16
Tao Su, Jing-Xuan Bai, Ying-Jie Chen, Xin-Ning Wang, Xiu-Qiong Fu, Ting Li, Hui Guo, Pei-Li Zhu, Yue Wang, Zhi-Ling Yu. An Ethanolic Extract of Ampelopsis Radix Exerts Anti-colorectal Cancer Effects and Potently Inhibits STAT3 Signaling In VitroFrontiers in Pharmacology 2017; 8 doi: 10.3389/fphar.2017.00227
17
Zhe Liu, Huan Wang, Lingnan Guan, Siyi Chen, Maode Lai. A novel small molecular STAT3 inhibitor, 5Br-6b, induces apoptosis and inhibits migration in colorectal cancer cellsAnti-Cancer Drugs 2018; 29(5): 402 doi: 10.1097/CAD.0000000000000605
18
Rong Lu, Yong-guo Zhang, Jun Sun. STAT3 activation in infection and infection-associated cancerMolecular and Cellular Endocrinology 2017; 451: 80 doi: 10.1016/j.mce.2017.02.023
19
Hua Xiong, Zhao-Fei Chen, Qin-Chuan Liang, Wan Du, Hui-Min Chen, Wen-Yu Su, Guo-Qiang Chen, Ze-Guang Han, Jing-Yuan Fang. Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signallingJournal of Cellular and Molecular Medicine 2009; 13(9b): 3668 doi: 10.1111/j.1582-4934.2009.00661.x
20
Takashi Uchiyama, Hirokazu Takahashi, Hiroki Endo, Eiji Sakai, Kunihiro Hosono, Yoji Nagashima, Atsushi Nakajima. IL-6 Plays Crucial Roles in Sporadic Colorectal Cancer through the Cytokine Networks including CXCL7Journal of Cancer Therapy 2012; 3(06): 874 doi: 10.4236/jct.2012.326112
21
Naveena B. Janakiram, Altaf Mohammed, Taylor Bryant, Misty Brewer, Laura Biddick, Stan Lightfoot, Mark L. Lang, Chinthalapally V. Rao. Adoptive transfer of regulatory T cells promotes intestinal tumorigenesis and is associated with decreased NK cells and IL-22 binding proteinMolecular Carcinogenesis 2015; 54(10): 986 doi: 10.1002/mc.22168
22
Chongqiang Zhao, Wenlong Wang, Wenying Yu, David Jou, Yina Wang, Haiyan Ma, Hui Xiao, Hua Qin, Cuntai Zhang, Jiagao Lü, Sheng Li, Chenglong Li, Jiayuh Lin, Li Lin. A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cellsOncotarget 2016; 7(11): 12917 doi: 10.18632/oncotarget.7338
23
Ting-Hong Ye, Fang-Fang Yang, Yong-Xia Zhu, Ya-Li Li, Qian Lei, Xue-Jiao Song, Yong Xia, Ying Xiong, Li-Dan Zhang, Ning-Yu Wang, Li-Feng Zhao, Hong-Feng Gou, Yong-Mei Xie, Sheng-Yong Yang, Luo-Ting Yu, Li Yang, Yu-Quan Wei. Inhibition of Stat3 signaling pathway by nifuroxazide improves antitumor immunity and impairs colorectal carcinoma metastasisCell Death & Disease 2018; 8(1): e2534 doi: 10.1038/cddis.2016.452
24
Wanlu Li, Mi-Ra Lee, Taeyeong Kim, Young Wan Kim, Mee-Yon Cho. Activated STAT3 may participate in tumor progression through increasing CD133/survivin expression in early stage of colon cancerBiochemical and Biophysical Research Communications 2018; 497(1): 354 doi: 10.1016/j.bbrc.2018.02.084
25
Jennifer Dien Bard, Pascal Gelebart, Mona Anand, Zoulika Zak, Samar A. Hegazy, Hesham M. Amin, Raymond Lai. IL-21 Contributes to JAK3/STAT3 Activation and Promotes Cell Growth in ALK-Positive Anaplastic Large Cell LymphomaThe American Journal of Pathology 2009; 175(2): 825 doi: 10.2353/ajpath.2009.080982
26
Shin-Yi Chung, Yen-Hsi Chen, Pei-Rong Lin, Ta-Chung Chao, Jung-Chen Su, Chung-Wai Shiau, Yeu Su. Two novel SHP-1 agonists, SC-43 and SC-78, are more potent than regorafenib in suppressing the in vitro stemness of human colorectal cancer cellsCell Death Discovery 2018; 4(1) doi: 10.1038/s41420-018-0084-z
27
Kun Ji, Mingxuan Zhang, Qi Chu, Yong Gan, Hui Ren, Liyan Zhang, Liwei Wang, Xiaoxiu Li, Wei Wang, Xianglin Shi. The Role of p-STAT3 as a Prognostic and Clinicopathological Marker in Colorectal Cancer: A Systematic Review and Meta-AnalysisPLOS ONE 2016; 11(8): e0160125 doi: 10.1371/journal.pone.0160125
28
Li Lin, David Jou, Yina Wang, Haiyan Ma, Tianshu Liu, James Fuchs, Pui-Kai Li, Jiagao Lü, Chenglong Li, Jiayuh Lin. STAT3 as a potential therapeutic target in ALDH+ and CD44+/CD24+ stem cell-like pancreatic cancer cellsInternational Journal of Oncology 2016; 49(6): 2265 doi: 10.3892/ijo.2016.3728
29
Hua Xiong, Wan Du, Tian-Tian Sun, Yan-Wei Lin, Ji-Lin Wang, Jie Hong, Jing-Yuan Fang. A positive feedback loop between STAT3 and cyclooxygenase-2 gene may contribute toHelicobacter pylori-associated human gastric tumorigenesisInternational Journal of Cancer 2014; 134(9): 2030 doi: 10.1002/ijc.28539
30
Vittoria Stigliano, Lupe Sanchez-Mete, Aline Martayan, Marcello Anti. Early-onset colorectal cancer: A sporadic or inherited disease?World Journal of Gastroenterology 2014; 20(35): 12420-12430 doi: 10.3748/wjg.v20.i35.12420
31
Shahab Uddin, Azhar R. Hussain, Omar S. Khan, Khawla S. Al-Kuraya. Role of dysregulated expression of leptin and leptin receptors in colorectal carcinogenesisTumor Biology 2014; 35(2): 871 doi: 10.1007/s13277-013-1166-4
32
Olorunseun O. Ogunwobi, Ian L. P. Beales. The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/AktInternational Journal of Colorectal Disease 2007; 22(4): 401 doi: 10.1007/s00384-006-0181-y
33
JIN YING, MASAHIKO TSUJII, JUMPEI KONDO, YOSHITO HAYASHI, MOTOHIKO KATO, TOMOFUMI AKASAKA, TAKUTA INOUE, ERI SHIRAISHI, TAHAHIRO INOUE, SATOSHI HIYAMA, YOSHIKI TSUJII, AKIRA MAEKAWA, SHOICHIRO KAWAI, TETSUJI FUJINAGA, MAEKAWA ARAKI, SHINICHIRO SHINZAKI, KENJI WATABE, TSUTOMU NISHIDA, HIDEKI IIJIMA, TETSUO TAKEHARA. The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cellsInternational Journal of Oncology 2015; 46(4): 1551 doi: 10.3892/ijo.2015.2851
34
Naveena B Janakiram, Chinthalapally V Rao. Molecular markers and targets for colorectal cancer preventionActa Pharmacologica Sinica 2008; 29(1): 1 doi: 10.1111/j.1745-7254.2008.00742.x
35
Noemí Eiró, Francisco J Vizoso. Inflammation and cancerWorld Journal of Gastrointestinal Surgery 2012; 4(3): 62-72 doi: 10.4240/wjgs.v4.i3.62
36
Shujie Hou, Yong Weon Yi, Hyo Jin Kang, Li Zhang, Hee Jeong Kim, Yali Kong, Yong Liu, Kan Wang, Hye-Sik Kong, Scott Grindrod, Insoo Bae, Milton L. Brown. Novel Carbazole Inhibits Phospho-STAT3 through Induction of Protein–Tyrosine Phosphatase PTPN6Journal of Medicinal Chemistry 2014; 57(15): 6342 doi: 10.1021/jm4018042
37
Jean-Philippe Spano, Gerard Milano, Clivier Rixe, Remi Fagard. JAK/STAT signalling pathway in colorectal cancer: A new biological target with therapeutic implicationsEuropean Journal of Cancer 2006; 42(16): 2668 doi: 10.1016/j.ejca.2006.07.006
38
Seung Woo Lee, Young Yong Ahn, Yon Soo Kim, Sang Beum Kang, Soon Woo Nam, Dong Soo Lee, Hyun Yong Jeong, Jin Man Kim. The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and AdenocarcinomaGut and Liver 2012; 6(1): 45 doi: 10.5009/gnl.2012.6.1.45
39
Mohamed M. Shareef, Maha M. Shamloula, Asem A. Elfert, Mohamed El-sawaf, Hanan H. Soliman. Expression of the signal transducer and activator of transcription factor 3 and Janus kinase 3 in colorectal carcinomas, colonic adenomas and ulcerative colitisArab Journal of Gastroenterology 2009; 10(1): 25 doi: 10.1016/j.ajg.2009.03.006
40
W.F. Qian, W.X. Guan, Y. Gao, J.F. Tan, Z.M. Qiao, H. Huang, C.L. Xia. Inhibition of STAT3 by RNA interference suppresses angiogenesis in colorectal carcinomaBrazilian Journal of Medical and Biological Research 2011; 44(12): 1222 doi: 10.1590/S0100-879X2011007500143
41
Hua Xiong, Wan Du, Yan-Jie Zhang, Jie Hong, Wen-Yu Su, Jie-Ting Tang, Ying-Chao Wang, Rong Lu, Jing-Yuan Fang. Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cellsMolecular Carcinogenesis 2012; 51(2): 174 doi: 10.1002/mc.20777
42
Yesol Bak, Taeho Kwon, In seon Bak, Jintae Hong, Dae-Yeul Yu, Do-Young Yoon. IL-32θ inhibits stemness and epithelial-mesenchymal transition of cancer stem cells via the STAT3 pathway in colon cancerOncotarget 2016; 7(6): 7307 doi: 10.18632/oncotarget.7007
43
Shengli Pan, Yingying Deng, Jun Fu, Yuhao Zhang, Zhijin Zhang, Xiaokun Ru, Xianju Qin. TRIM52 promotes colorectal cancer cell proliferation through the STAT3 signalingCancer Cell International 2019; 19(1) doi: 10.1186/s12935-019-0775-4
44
Ching-Shu Lai, Mei-Ling Tsai, An-Chin Cheng, Shiming Li, Chih-Yu Lo, Yu Wang, Hang Xiao, Chi-Tang Ho, Ying-Jan Wang, Min-Hsiung Pan. Chemoprevention of colonic tumorigenesis by dietary hydroxylated polymethoxyflavones in azoxymethane-treated miceMolecular Nutrition & Food Research 2011; 55(2): 278 doi: 10.1002/mnfr.201000224
45
Rakesh Naidu, Lim Vin Nee, Mak Joon Wah, Kevin Moissinac, A. Rahman A. Jamal, Isa Mohd Rose, Yunus Gul Alif Gul, Patricia Lim Kim Chooi, Gregory Tan Jin San. Protein Expression of STAT3, pSTAT3, MMP-7 and VEGF in Colorectal Adenocarcinoma: An Immunohistochemical StudyJournal of Cancer Therapy 2014; 5(13): 1175 doi: 10.4236/jct.2014.513119
46
Dora Colussi, Giovanni Brandi, Franco Bazzoli, Luigi Ricciardiello. Molecular Pathways Involved in Colorectal Cancer: Implications for Disease Behavior and PreventionInternational Journal of Molecular Sciences 2013; 14(8): 16365 doi: 10.3390/ijms140816365
47
Jufeng Zhang, Xia Luo, Huiming Li, Ling Deng, Ying Wang. Genome-Wide Uncovering of STAT3-Mediated miRNA Expression Profiles in Colorectal Cancer Cell LinesBioMed Research International 2014; 2014: 1 doi: 10.1155/2014/187105
48
Ewa Nowakowska-Zajdel, Urszula Mazurek, Malgorzata Stachowicz, Elzbieta Niedworok, Edyta Fatyga, Małgorzata Muc-Wierzgoń. Cellular Signal Transduction Pathways by Leptin in Colorectal Cancer Tissue: Preliminary ResultsISRN Endocrinology 2011; 2011: 1 doi: 10.5402/2011/575397
49
Joaquina Baranda, Stephen Williamson. The new paradigm in the treatment of colorectal cancer: are we hitting the right target?Expert Opinion on Investigational Drugs 2007; 16(3): 311 doi: 10.1517/13543784.16.3.311
50
Jie Zheng, Mi Hee Park, Dong Ju Son, Min Gi Choi, Jeong Soon Choi, Kyung Tak Nam, Hae Deun Kim, Kevin Rodriguez, Benjamin Gann, Young Wan Ham, Sang Bae Han, Jin Tae Hong. (E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in miceOncotarget 2015; 6(39): 41929 doi: 10.18632/oncotarget.5861
51
Haseeb Ahsan, Moammir Hasan Aziz, Nihal Ahmad. Ultraviolet B exposure activates Stat3 signaling via phosphorylation at tyrosine705 in skin of SKH1 hairless mouse: A target for the management of skin cancer?Biochemical and Biophysical Research Communications 2005; 333(1): 241 doi: 10.1016/j.bbrc.2005.05.106
52
Wei Shi, Dan Yan, Chongqiang Zhao, Miaomiao Xiao, Yina Wang, Haiyan Ma, Tianshu Liu, Hua Qin, Cuntai Zhang, Chenglong Li, Jiayuh Lin, Sheng Li, Jiagao Lv, Li Lin. Inhibition of IL-6/STAT3 signaling in human cancer cells using EvistaBiochemical and Biophysical Research Communications 2017; 491(1): 159 doi: 10.1016/j.bbrc.2017.07.067
53
Yun Tian, Ying Ye, Wei Gao, Hong Chen, Ting Song, Daqing Wang, Xiaoyun Mao, Changshan Ren. Aspirin promotes apoptosis in a murine model of colorectal cancer by mechanisms involving downregulation of IL-6–STAT3 signaling pathwayInternational Journal of Colorectal Disease 2011; 26(1): 13 doi: 10.1007/s00384-010-1060-0
54
Mikio Tomida, Hideki Ohtake, Takashi Yokota, Yasuhito Kobayashi, Masafumi Kurosumi. Stat3 up-regulates expression of nicotinamide N-methyltransferase in human cancer cellsJournal of Cancer Research and Clinical Oncology 2008; 134(5): 551 doi: 10.1007/s00432-007-0318-6
55
Li Lin, James Fuchs, Chenglong Li, Veronica Olson, Tanios Bekaii-Saab, Jiayuh Lin. STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cellsBiochemical and Biophysical Research Communications 2011; 416(3-4): 246 doi: 10.1016/j.bbrc.2011.10.112
56
Songhee Han, Ae Jin Jeong, Heejung Yang, Kyo Bin Kang, Haeri Lee, Eun Hee Yi, Byung-Hak Kim, Chung-Hyun Cho, Jin Woong Chung, Sang Hyun Sung, Sang-Kyu Ye. Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cellsJournal of Ethnopharmacology 2016; 194: 83 doi: 10.1016/j.jep.2016.08.039
57
Elisabeth Ziesché, Malte Bachmann, Hartmut Kleinert, Josef Pfeilschifter, Heiko Mühl. The Interleukin-22/STAT3 Pathway Potentiates Expression of Inducible Nitric-oxide Synthase in Human Colon Carcinoma CellsJournal of Biological Chemistry 2007; 282(22): 16006 doi: 10.1074/jbc.M611040200
58
Chadrashekar Kagepura Thammaiah, Shankar Jayaram. Role of let-7 family microRNA in breast cancerNon-coding RNA Research 2016; 1(1): 77 doi: 10.1016/j.ncrna.2016.10.003
59
Ian L.P. Beales, O. Ogunwobi. Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathwaysMolecular and Cellular Endocrinology 2006; 247(1-2): 140 doi: 10.1016/j.mce.2005.12.050
60
Rathindranath Baral, Anamika Bose, Chinmoyee Ray, Sonali Paul, Smarajit Pal, Enamul Haque, Bhagawan Mishra, Debolina Pal, Jatin Kumar Nagpal, Chinmay Kumar Panda, Bibhu Ranjan Das. Association of early phase of colorectal carcinogenesis with STAT3 activation and its relevance in apoptosis regulationExperimental and Molecular Pathology 2009; 87(1): 36 doi: 10.1016/j.yexmp.2009.03.002
61
Ujjal Das, Krishnendu Manna, Arghya Adhikary, Snehasis Mishra, Krishna Das Saha, Rakhi Dey Sharma, Biswanath Majumder, Sanjit Dey. Ferulic acid enhances the radiation sensitivity of lung and liver carcinoma cells by collapsing redox homeostasis: mechanistic involvement of Akt/p38 MAPK signalling pathwayFree Radical Research 2019; 53(9-10): 944 doi: 10.1080/10715762.2019.1655559
62
Fangfang Yang, Tinghong Ye, Zhihao Liu, Aiping Fang, Yi Luo, Wei wei, Yujue Li, Yali Li, Anqi Zeng, Yuanle Deng, Hongfeng Gou, Yongmei Xie, Yiwen Zhang, Yuquan Wei. Niclosamide induces colorectal cancer apoptosis, impairs metastasis and reduces immunosuppressive cells in vivoRSC Advances 2016; 6(107): 106019 doi: 10.1039/C6RA21533E