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For: Grattagliano I, Bonfrate L, Diogo CV, Wang HH, Wang DQ, Portincasa P. Biochemical mechanisms in drug-induced liver injury: Certainties and doubts. World J Gastroenterol 2009; 15(39): 4865-4876 [PMID: 19842215 DOI: 10.3748/wjg.15.4865]
URL: https://www.wjgnet.com/1007-9327/full/v15/i39/4865.htm
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Hanène Ben Miled, Zaineb Ben Barka, Dorsaf Hallègue, Karima Lahbib, Mohamed Ladjimi, Mounira Tlili, Mohsen Sakly, Khémais Ben Rhouma, Riadh Ksouri, Olfa Tebourbi. Hepatoprotective activity of Rhus oxyacantha root cortex extract against DDT-induced liver injury in ratsBiomedicine & Pharmacotherapy 2017; 90: 203 doi: 10.1016/j.biopha.2017.03.063
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Emilio Molina-Molina, Harshitha Shanmugam, Domenica Di Palo, Ignazio Grattagliano, Piero Portincasa. Mitochondrial RegulationMethods in Molecular Biology 2021; 2310: 179 doi: 10.1007/978-1-0716-1433-4_11
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Robert A. Ettlin, Junji Kuroda, Stephanie Plassmann, Makoto Hayashi, David E. Prentice. Successful Drug Development Despite Adverse Preclinical Findings Part 2: ExamplesJournal of Toxicologic Pathology 2010; 23(4): 213 doi: 10.1293/tox.23.213
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Diagnostic Imaging: Gastrointestinal2015; : 638 doi: 10.1016/B978-0-323-37755-3.50200-2
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Nadezda Apostolova. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging2014; : 81 doi: 10.1016/B978-0-12-405529-2.00005-6
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Andrés Tabernilla, Bruna dos Santos Rodrigues, Alanah Pieters, Anne Caufriez, Kaat Leroy, Raf Van Campenhout, Axelle Cooreman, Ana Rita Gomes, Emma Arnesdotter, Eva Gijbels, Mathieu Vinken. In Vitro Liver Toxicity Testing of Chemicals: A Pragmatic ApproachInternational Journal of Molecular Sciences 2021; 22(9): 5038 doi: 10.3390/ijms22095038
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Alejandra Cano Paniagua, Pedro Amariles. Pharmacokinetics and Adverse Effects of Drugs - Mechanisms and Risks Factors2018;  doi: 10.5772/intechopen.72005
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Ignazio Grattagliano, Leonilde Bonfrate, Michele Lorusso, Luigi Castorani, Ornella de Bari, Piero Portincasa. Mitochondrial RegulationMethods in Molecular Biology 2015; 1241: 137 doi: 10.1007/978-1-4939-1875-1_12
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Yun Wei, Meixia Liu, Jiangang Liu, Hao Li. Influence Factors on the Hepatotoxicity of Polygoni Multiflori RadixEvidence-Based Complementary and Alternative Medicine 2019; 2019: 1 doi: 10.1155/2019/5482896
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María Teresa Donato, Laia Tolosa. High-Content Screening for the Detection of Drug-Induced Oxidative Stress in Liver CellsAntioxidants 2021; 10(1): 106 doi: 10.3390/antiox10010106
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Debajyoti Bhattacharya, Prerona Biswas, Somnath Gangopadhyay, Mausumi Sikdar Bhakta. Ameliorative effects of high-protein diet on hepatotoxic alterations in Swiss albino mice exposed to mobile phone radiationIndian Journal of Physiology and Pharmacology 2021; 64: 258 doi: 10.25259/IJPP_141_2020
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Angelica Kresnamurti, Dita Nurlita Rakhma, Amitasari Damayanti, Septiyan Dwi Santoso, Enggar Restryarto, Wifqi Hadinata, Iwan Sahrial Hamid. AST/ALT levels, MDA, and liver histopathology of Echinometra mathaei ethanol extract on paracetamol-induced hepatotoxicity in ratsJournal of Basic and Clinical Physiology and Pharmacology 2021; 32(4): 511 doi: 10.1515/jbcpp-2020-0420
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Russell C. Cattley, John M. Cullen. Haschek and Rousseaux's Handbook of Toxicologic Pathology2013; : 1509 doi: 10.1016/B978-0-12-415759-0.00045-5
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Mehboob Ali, Sagheer Ahmed Khan, Peter S. Chang, Rizwanul Haque, Kanchan Bhatia, Saif Ahmad. Habb-e-Asgand, polyherbal Unani formulation, protects liver and antioxidative enzymes against paracetamol induced hepatotoxicityPharmaceutical Biology 2014; 52(4): 506 doi: 10.3109/13880209.2013.863949
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Tomáš Smutný, Riina Harjumäki, Liisa Kanninen, Marjo Yliperttula, Petr Pávek, Yan-Ru Lou. A feasibility study of the toxic responses of human induced pluripotent stem cell-derived hepatocytes to phytochemicalsToxicology in Vitro 2018; 52: 94 doi: 10.1016/j.tiv.2018.06.012
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James Rathman, Chihae Yang, J. Vinicius Ribeiro, Aleksandra Mostrag, Shraddha Thakkar, Weida Tong, Bryan Hobocienski, Oliver Sacher, Tomasz Magdziarz, Bruno Bienfait. Development of a Battery of In Silico Prediction Tools for Drug-Induced Liver Injury from the Vantage Point of Translational Safety AssessmentChemical Research in Toxicology 2021; 34(2): 601 doi: 10.1021/acs.chemrestox.0c00423
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Arthur Shiyovich, Lior Nesher, Ignacio Sztarkier. Toxic Hepatitis Induced by Gymnema sylvestre, a Natural Remedy for Type 2 Diabetes MellitusThe American Journal of the Medical Sciences 2010; 340(6): 514 doi: 10.1097/MAJ.0b013e3181f41168
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Martin Wehling. Non-steroidal anti-inflammatory drug use in chronic pain conditions with special emphasis on the elderly and patients with relevant comorbidities: management and mitigation of risks and adverse effectsEuropean Journal of Clinical Pharmacology 2014; 70(10): 1159 doi: 10.1007/s00228-014-1734-6
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John O. Ojowu, Alfred P. Agi, Etim E. Etim, Joseph O. Adikwu, Erhunmwunsee D. Avan. Investigating the Protective Effect of Lawsonia inermis Extract on Liver and Kidney Function in Carbon Tetrachloride (CCl4) Induced RatsEgyptian Journal of Basic and Clinical Pharmacology 2020; 10 doi: 10.32527/2020/101442
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Mathieu Vinken, Bas J. Blaauboer. In vitro testing of basal cytotoxicity: Establishment of an adverse outcome pathway from chemical insult to cell deathToxicology in Vitro 2017; 39: 104 doi: 10.1016/j.tiv.2016.12.004
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Sukanta Jash, Samit Adhya. Induction of muscle regeneration by RNA‐mediated mitochondrial restorationThe FASEB Journal 2012; 26(10): 4187 doi: 10.1096/fj.11-203232
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Seyed Fazel Nabavi, Maria Daglia, Akbar Hajizadeh Moghaddam, Solomon Habtemariam, Seyed Mohammad Nabavi. Curcumin and Liver Disease: from Chemistry to MedicineComprehensive Reviews in Food Science and Food Safety 2014; 13(1): 62 doi: 10.1111/1541-4337.12047
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Mohamed Elsayed Kelany, Mohamed Abdelmohsen Abdallah. Protective effects of combined β-caryophyllene and silymarin against ketoprofen-induced hepatotoxicity in ratsCanadian Journal of Physiology and Pharmacology 2016; 94(7): 739 doi: 10.1139/cjpp-2015-0607
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Ruo-Lan Li, Feng Gao, Shu-Ting Yan, Li Ou, Ming Li, Lin Chen, Pei-Feng Wei, Zong-Qiang Gao. Effects of Different Processed Products of Polygonum multiflorum on the LiverEvidence-Based Complementary and Alternative Medicine 2020; 2020: 1 doi: 10.1155/2020/5235271
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Patrick J. Shaw, Patricia E. Ganey, Robert A. Roth. Idiosyncratic Drug-Induced Liver Injury and the Role of Inflammatory Stress with an Emphasis on an Animal Model of Trovafloxacin HepatotoxicityToxicological Sciences 2010; 118(1): 7 doi: 10.1093/toxsci/kfq168
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Salman R. Khetani, Chitra Kanchagar, Okechukwu Ukairo, Stacy Krzyzewski, Amanda Moore, Julianne Shi, Simon Aoyama, Michael Aleo, Yvonne Will. Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in HumansToxicological Sciences 2013; 132(1): 107 doi: 10.1093/toxsci/kfs326
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Brenton R. Ware, Dustin R. Berger, Salman R. Khetani. Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human HepatocytesToxicological Sciences 2015; 145(2): 252 doi: 10.1093/toxsci/kfv048
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Z. Zazuli, M. I. Barliana, U. A. Mulyani, D. A. Perwitasari, H. Ng, R. Abdulah. Polymorphism of PXR gene associated with the increased risk of drug-induced liver injury in Indonesian pulmonary tuberculosis patientsJournal of Clinical Pharmacy and Therapeutics 2015; 40(6): 680 doi: 10.1111/jcpt.12325
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Akram Eidi, Pejman Mortazavi, Jalal Zarringhalam Moghadam, Parisa Mousavi Mardani. Hepatoprotective effects ofPortulaca oleraceaextract against CCl4-induced damage in ratsPharmaceutical Biology 2015; 53(7): 1042 doi: 10.3109/13880209.2014.957783
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Jeffrey C. Wolf, James R. Wheeler. A critical review of histopathological findings associated with endocrine and non-endocrine hepatic toxicity in fish modelsAquatic Toxicology 2018; 197: 60 doi: 10.1016/j.aquatox.2018.01.013
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John Oludele Olanlokun, Olusola Bodede, Gerhard Prinsloo, Olufunso Olabode Olorunsogo. Comparative antimalarial, toxicity and mito-protective effects of Diospyros mespiliformis Hochst. ex A. DC. and Mondia whitei (Hook.f.) Skeels on Plasmodium berghei infection in miceJournal of Ethnopharmacology 2021; 268: 113585 doi: 10.1016/j.jep.2020.113585
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Maria Grazia Anelli, Crescenzio Scioscia, Ignazio Grattagliano, Giovanni Lapadula. Old and New Antirheumatic Drugs and the Risk of HepatotoxicityTherapeutic Drug Monitoring 2012; 34(6): 622 doi: 10.1097/FTD.0b013e31826a6306
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M.G.L. Elferink, P. Olinga, E.M. van Leeuwen, S. Bauerschmidt, J. Polman, W.G. Schoonen, S.H. Heisterkamp, G.M.M. Groothuis. Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genesToxicology and Applied Pharmacology 2011; 253(1): 57 doi: 10.1016/j.taap.2011.03.010
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Carla W Brady. Liver disease in menopauseWorld Journal of Gastroenterology 2015; 21(25): 7613-7620 doi: 10.3748/wjg.v21.i25.7613
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Xiaoting Jin, Huilan Su, Guobin Ding, Zhendong Sun, Zhuoyu Li. Exposure to ambient fine particles causes abnormal energy metabolism and ATP decrease in lung tissuesChemosphere 2019; 224: 29 doi: 10.1016/j.chemosphere.2019.02.116
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Mallikarjuna Rao Talluri, Rajananda Swamy Tadi, Ganga Rao Battu. Thioacetamide-induced acute liver toxicity in rats treated with Balanites roxburghii extractsJournal of Acute Disease 2016; 5(5): 413 doi: 10.1016/j.joad.2016.08.009
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J M Harrold, M Ramanathan, D E Mager. Network-Based Approaches in Drug Discovery and Early DevelopmentClinical Pharmacology & Therapeutics 2013; 94(6): 651 doi: 10.1038/clpt.2013.176
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Heena Tabassum, Suhel Parvez, Syed Tazeen Pasha, Basu Dev Banerjee, Sheikh Raisuddin. Protective effect of lipoic acid against methotrexate-induced oxidative stress in liver mitochondriaFood and Chemical Toxicology 2010; 48(7): 1973 doi: 10.1016/j.fct.2010.04.047
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Li Tang, Yun-lan Li, Rui Ge, Qing-Shan Li. Oxidative stress in di-n-butyl-di-(4-chlorobenzohydroxamato)tin (IV)-induced hepatotoxicity determined by proteomic profilesToxicology Letters 2012; 213(2): 167 doi: 10.1016/j.toxlet.2012.06.008
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Chinthamony Arul Raj, Paramasivam Ragavendran, Dominic Sophia, Thangarajan Starlin, Muthian Ahalliya Rathi, Velliyur Kanniappan Gopalakrishnan. Evaluation of in vitro enzymatic and non-enzymatic antioxidant properites of leaf extract from Alpinia Purpurata (Vieill.) K. Schum.Chinese Journal of Integrative Medicine 2016; 22(9): 691 doi: 10.1007/s11655-014-1762-1
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Herson González-Ponce, Ana Rincón-Sánchez, Fernando Jaramillo-Juárez, Han Moshage. Natural Dietary Pigments: Potential Mediators against Hepatic Damage Induced by Over-The-Counter Non-Steroidal Anti-Inflammatory and Analgesic DrugsNutrients 2018; 10(2): 117 doi: 10.3390/nu10020117
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Magd A. Kotb. Molecular Mechanisms of Ursodeoxycholic Acid Toxicity & Side Effects: Ursodeoxycholic Acid Freezes Regeneration & Induces Hibernation ModeInternational Journal of Molecular Sciences 2012; 13(7): 8882 doi: 10.3390/ijms13078882
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Elizabeth McInnes. Pathology of Taxicologists2017; : 72 doi: 10.1002/9781118755174.ch5
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Franziska Wewering, Florent Jouy, Dirk K. Wissenbach, Scarlett Gebauer, Matthias Blüher, Rolf Gebhardt, Ralph Pirow, Martin von Bergen, Stefan Kalkhof, Andreas Luch, Sebastian Zellmer. Characterization of chemical-induced sterile inflammation in vitro: application of the model compound ketoconazole in a human hepatic co-culture systemArchives of Toxicology 2017; 91(2): 799 doi: 10.1007/s00204-016-1686-y
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Nevena Todorović, Nada Tomanović, Peter Gass, Dragana Filipović. Olanzapine modulation of hepatic oxidative stress and inflammation in socially isolated ratsEuropean Journal of Pharmaceutical Sciences 2016; 81: 94 doi: 10.1016/j.ejps.2015.10.010
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Cheau Yih Tan, Tzuen Yih Saw, Chee Wai Fong, Han Kiat Ho. Comparative hepatoprotective effects of tocotrienol analogs against drug-induced liver injuryRedox Biology 2015; 4: 308 doi: 10.1016/j.redox.2015.01.013
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Lin Niu, Yunlan Li, Qingshan Li. Medicinal properties of organotin compounds and their limitations caused by toxicityInorganica Chimica Acta 2014; 423: 2 doi: 10.1016/j.ica.2014.05.007
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Timothy E. H. Allen, Jonathan M. Goodman, Steve Gutsell, Paul J. Russell. Defining Molecular Initiating Events in the Adverse Outcome Pathway Framework for Risk AssessmentChemical Research in Toxicology 2014; 27(12): 2100 doi: 10.1021/tx500345j
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Ludi Jiang, Yusu He, Yanling Zhang. Prediction of hepatotoxicity of traditional Chinese medicine compounds by support vector machine approach2014 8th International Conference on Systems Biology (ISB) 2014; : 27 doi: 10.1109/ISB.2014.6990426
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Jeffrey D. Peterson. Nutraceuticals2021; : 363 doi: 10.1016/B978-0-12-821038-3.00025-2
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Ahmad Sharanek, Audrey Burban, Lydie Humbert, Pamela Bachour-El Azzi, Neuza Felix-Gomes, Dominique Rainteau, Andre Guillouzo. Cellular Accumulation and Toxic Effects of Bile Acids in Cyclosporine A-Treated HepaRG HepatocytesToxicological Sciences 2015; 147(2): 573 doi: 10.1093/toxsci/kfv155
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Laia Tolosa, Sandra Pinto, M. Teresa Donato, Agustín Lahoz, José V. Castell, J. Enrique O’Connor, M. José Gómez-Lechón. Development of a Multiparametric Cell-based Protocol to Screen and Classify the Hepatotoxicity Potential of DrugsToxicological Sciences 2012; 127(1): 187 doi: 10.1093/toxsci/kfs083
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Hong Yun Kim, Cheol Park, Yung Hyun Choi, Won-Deok Hwang. The Protective Effect of Ethanol Extract of Polygalae Radix against Oxidative Stress-Induced DNA Damage and Apoptosis in Chang Liver CellsJournal of Korean Medicine for Obesity Research 2019; 19(1): 1 doi: 10.15429/jkomor.2019.19.1.1
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Lyvia Lintzmaier Petiz, Amanda do Rocio Andrade Pires, Aurea Echevarria, Cláudio Eduardo Rodrigues-Santos, Maria Eliane Merlin Rocha, Alexandra Acco, Silvia Maria Suter Correia Cadena. Effects of a new antiprotozoal drug, N,N′ -diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondriaChemico-Biological Interactions 2018; 279: 34 doi: 10.1016/j.cbi.2017.11.006
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Pinar Erkekoglu. Cellular and Molecular Aspects of Drug-Induced Liver Toxicity: Recent Prominent MechanismsMOJ Toxicology 2015; 1(5) doi: 10.15406/mojt.2015.01.00023
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Afolabi C. Akinmoladun, Comfort Odunayo Oladejo, Sunday Solomon Josiah, Courage Dele Famusiwa, Olubukola Benedicta Ojo, M. Tolulope Olaleye. Catechin, quercetin and taxifolin improve redox and biochemical imbalances in rotenone-induced hepatocellular dysfunction: Relevance for therapy in pesticide-induced liver toxicity?Pathophysiology 2018; 25(4): 365 doi: 10.1016/j.pathophys.2018.07.002
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David Q.‐H. Wang, Piero Portincasa, Brent A. Neuschwander‐Tetri. Comprehensive Physiology2013; : 1493 doi: 10.1002/cphy.c130001
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Che-Chang Chan, Ling-Yi Cheng, Chin-Lung Lin, Yi-Hsiang Huang, Han-Chieh Lin, Fa-Yauh Lee. The protective role of natural phytoalexin resveratrol on inflammation, fibrosis and regeneration in cholestatic liver injuryMolecular Nutrition & Food Research 2011; 55(12): 1841 doi: 10.1002/mnfr.201100374
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Baimei Zeng, Ling Yuan, Jun Chu, Yanqing Yang, Shide Lin. Challenges in early identification of causes and treatment of cholestasis in patients with hyperthyroidism: a case report and literature reviewJournal of International Medical Research 2020; 48(3): 030006051989101 doi: 10.1177/0300060519891018
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Emmanuel Simon, P. Aswini, V. B. Sameer Kumar, Gokuldas Mankadath. Curcumin and its synthetic analogue dimethoxycurcumin differentially modulates antioxidant status of normal human peripheral blood mononuclear cellsFree Radical Research 2018; 52(5): 583 doi: 10.1080/10715762.2018.1455002
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Jacob Kehinde Akintunde, Olakunle Enock Bolarin. Research on garlic capsule and selenium-vitamin A, vitamin B, vitamin C applied in therapy of acute hepatocellular damage in a rat modelJournal of Acute Disease 2015; 4(4): 298 doi: 10.1016/j.joad.2015.06.008
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Agnieszka Korolczuk, Kinga Caban, Magdalena Amarowicz, Grażyna Czechowska, Joanna Irla-Miduch. Oxidative Stress and Liver Morphology in Experimental Cyclosporine A-Induced HepatotoxicityBioMed Research International 2016; 2016: 1 doi: 10.1155/2016/5823271
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Henrik Cordes, Christoph Thiel, Vanessa Baier, Lars M. Blank, Lars Kuepfer. Integration of genome-scale metabolic networks into whole-body PBPK models shows phenotype-specific cases of drug-induced metabolic perturbationnpj Systems Biology and Applications 2018; 4(1) doi: 10.1038/s41540-018-0048-1
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Arvind Pradip, Daniella Steel, Susanna Jacobsson, Gustav Holmgren, Magnus Ingelman-Sundberg, Peter Sartipy, Petter Björquist, Inger Johansson, Josefina Edsbagge. High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and PhospholipidosisStem Cells International 2016; 2016: 1 doi: 10.1155/2016/2475631
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Laia Tolosa, Idania Rodeiro, M Teresa Donato, José A Herrera, René Delgado, José V Castell, M José Gómez-Lechón. Multiparametric evaluation of the cytoprotective effect of the Mangifera indica L. stem bark extract and mangiferin in HepG2 cellsJournal of Pharmacy and Pharmacology 2013; 65(7): 1073 doi: 10.1111/jphp.12071
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Nga T. T. Tham, So-Ryeon Hwang, Ji-Hyun Bang, Hee Yi, Young-Il Park, Seok-Jin Kang, Hwan-Goo Kang, Yong-Sang Kim, Hyun-Ok Ku. High-content analysis of in vitro hepatocyte injury induced by various hepatotoxicantsJournal of Veterinary Science 2019; 20(1): 34 doi: 10.4142/jvs.2019.20.1.34
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Ana S. Serras, Joana S. Rodrigues, Madalena Cipriano, Armanda V. Rodrigues, Nuno G. Oliveira, Joana P. Miranda. A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology StudiesFrontiers in Cell and Developmental Biology 2021; 9 doi: 10.3389/fcell.2021.626805
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Bechan Sharma, Shweta Singh, Sunil Kumar Jaiswal, Nikhat Jamal Siddiqi. Regulation of Membrane Na+-K+ ATPase2016; : 173 doi: 10.1007/978-3-319-24750-2_10
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Pardeep Kumar, R. K. Kale, Najma Zaheer Baquer. Estradiol Modulates Membrane-Linked ATPases, Antioxidant Enzymes, Membrane Fluidity, Lipid Peroxidation, and Lipofuscin in Aged Rat LiverJournal of Aging Research 2011; 2011: 1 doi: 10.4061/2011/580245