Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Feb 4, 2015; 4(1): 77-88
Published online Feb 4, 2015. doi: 10.5492/wjccm.v4.i1.77
Published online Feb 4, 2015. doi: 10.5492/wjccm.v4.i1.77
Utility of flexible fiberoptic bronchoscopy for critically ill pediatric patients: A systematic review
Aida Field-Ridley, Viyeka Sethi, Shweta Murthi, Kiran Nandalike, Su-Ting T Li, Department of Pediatrics, University of California Davis, Sacramento, CA 95618, United States
Author contributions: All authors contributed to this manuscript.
Supported by The National Center for Advancing Translational Sciences, National Institutes of Health, No. UL1 TR000002 (to Dr. Field-Ridley).
Conflict-of-interest: The authors have no conflicts of interest to disclose.
Data sharing: Technical appendix, statistical code, and dataset available from the corresponding author at su-ting.li@ucdmc.ucdavis.edu.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Su-Ting T Li, MD, MPH, Department of Pediatrics, University of California Davis, 2516 Stockton Blvd, Sacramento, CA 95618, United States. su-ting.li@ucdmc.ucdavis.edu
Telephone: +1-916-7342428 Fax: +1-916-7340342
Received: October 18, 2014
Peer-review started: October 21, 2014
First decision: November 27, 2014
Revised: December 16, 2014
Accepted: January 9, 2015
Article in press: January 12, 2015
Published online: February 4, 2015
Peer-review started: October 21, 2014
First decision: November 27, 2014
Revised: December 16, 2014
Accepted: January 9, 2015
Article in press: January 12, 2015
Published online: February 4, 2015
Core Tip
Core tip: Flexible fiberoptic bronchoscopy (FFB) is effective and safe for diagnostic and therapeutic use among critically ill pediatric patients. FFB led to change in management in 28.9% of patients, with a diagnostic yield of 82%. Bronchoalveolar lavage obtained during FFB may assist with identifying infectious organisms (25.7%) and optimizing antimicrobial therapy (19.1%). FFB had therapeutic benefit with removal of mucus plugs or resolution of atelectasis in 60.3%. The majority of reported adverse events were transient and included hypotension, hypoxia and/or bradycardia requiring minimal intervention.