Multidisciplinary discussion and management of synchronous colorectal liver metastases: A single center study in China

Table 5 Univariate and multivariate analyses of risk factors associated with 5-year overall survival

	n (%)	Univariate			Multivariate
		HR	95%CI	P value	HR	95%CI	P value
Age > 75	61 (23.28)	3.471	2.532-4.758	0.000	2.040	1.322-3.149	0.001
Sex (male)	133 (50.76)	0.938	0.721-1.221	0.938
BMI > 28	46 (17.56)	0.951	0.679-1.331	0.769
CEA > 5 ng/mL	125 (47.71)	2.446	1.872-3.195	0.000	2.516	1.847-3.428	0.000
Colon primary	118 (45.04)	1.349	1.035-1.757	0.027	0.828	0.622-1.102	0.195
Mucinous adenocarcinoma	36 (13.74)	0.792	0.529-1.184	0.256
Poor differentiation	37 (14.12)	1.102	0.758-1.603	0.611
Primary tumor category ≥ T3	202 (77.10)	0.969	0.710-1.322	0.841
Primary LN involvement	178 (67.94)	1.567	1.175-2.088	0.002	1.143	0.835-1.566	0.404
Multiple liver metastases	210 (80.15)	3.852	2.592-5.725	0.000	2.563	1.671-3.932	0.000
MDT	93 (35.50)	0.667	0.504-0.884	0.005	0.709	0.527-0.954	0.023
Chemotherapy	193 (73.66)	0.203	0.147-0.281	0.000	0.591	0.388-0.900	0.014
Curative resection	67 (25.57)	0.091	0.058-0.144	0.000	0.111	0.069-0.178	0.000

HR: Hazards ratio; CI: Confidence interval; BMI: Body mass index; CEA: Carcinoembryonic antigen; MDT: Multidisciplinary team; LN: Lymph node.