Multidisciplinary discussion and management of synchronous colorectal liver metastases: A single center study in China

Table 4 Univariate and multivariate analyses of risk factors associated with 1-year overall survival

	n (%)	Univariate			Multivariate
		HR	95%CI	P value	HR	95%CI	P value
Age > 75	61 (23.28)	3.533	2.44-5.11	0.000	2.065	1.257-3.393	0.004
Sex (male)	133 (50.76)	0.845	0.590-1.211	0.358
BMI > 28	46 (17.56)	0.765	0.468-1.250	0.285
CEA > 5 ng/mL	125 (47.71)	7.296	4.674-11.391	0.000	5.308	3.262-8.638	0.000
Colon primary	118 (45.04)	1.283	0.896-1.838	0.174	1.058	0.724-1.544	0.772
Mucinous adenocarcinoma	36 (13.74)	0.863	0.502-1.482	0.593
Poor differentiation	37 (14.12)	1.282	0.793-2.073	0.311
Primary tumor category ≥ T3	202 (77.10)	1.284	0.820-2.009	0.274
Primary LN involvement	178 (67.94)	3.336	2.061-5.400	0.000	1.948	1.156-3.281	0.012
Multiple liver metastases	210 (80.15)	13.97	4.44-43.97	0.000	4.747	1.470-15.333	0.009
MDT	93 (35.50)	0.53	0.353-0.801	0.003	0.572	0.374-0.874	0.010
chemotherapy	193 (73.66)	0.239	0.166-0.344	0.000	0.874	0.539-1.418	0.587
Curative resection	67 (25.57)	0.016	0.002-0.114	0.000	0.031	0.004-0.227	0.001

HR: Hazards ratio; CI: Confidence interval; BMI: Body mass index; CEA: Carcinoembryonic antigen; MDT: Multidisciplinary team; LN: Lymph node.