Comprehensive bioinformatic analysis of mind bomb 1 gene in stomach adenocarcinoma

Table 1 Demographic and clinicopathological parameters of patients with gastric cancer with high and low expression of mind bomb 1 in The Cancer Genome Atlas-stomach adenocarcinoma, n (%)

Characteristics	Total	Low expression of MIB1	High expression of MIB1	P value
T stage				0.017
T1	19 (5.2)	11 (3.0)	8 (2.2)
T2	80 (21.8)	37 (10.1)	43 (11.7)
T3	168 (45.8)	99 (27.0)	69 (18.8)
T4	100 (27.2)	40 (10.9)	60 (16.3)
N stage				0.433
N0	111 (31.1)	61 (17.1)	50 (14.0)
N1	97 (27.2)	49 (13.7)	48 (13.4)
N2	75 (21.0)	32 (9.0)	43 (12.0)
N3	74 (20.7)	38 (10.6)	36 (10.1)
M stage				1.000
M0	330 (93.0)	164 (46.2)	166 (46.8)
M1	25 (7.0)	12 (3.4)	13 (3.7)
Pathologic stage				0.032
Stage I	53 (15.1)	24 (6.8)	29 (8.2)
Stage II	111 (31.5)	69 (19.6)	42 (11.9)
Stage III	150 (42.6)	72 (20.5)	78 (22.2)
Stage IV	38 (10.8)	15 (4.3)	23 (6.5)
Gender				0.884
Female	134 (35.7)	68 (18.1)	66 (17.6)
Male	241 (64.3)	119 (31.7)	122 (32.5)
Histological type				0.448
Diffuse type	63 (16.8)	36 (9.6)	27 (7.2)
Mucinous type	19 (5.1)	11 (2.9)	8 (2.1)
Not otherwise specified	207 (55.3)	103 (27.5)	104 (27.8)
Papillary type	5 (1.3)	1 (0.3)	4 (1.1)
Signet ring type	11 (2.9)	4 (1.1)	7 (1.9)
Tubular type	69 (18.4)	32 (8.6)	37 (9.9)
Histologic grade				0.305
G1	10 (2.7)	4 (1.1)	6 (1.6)
G2	137 (37.4)	63 (17.2)	74 (20.2)
G3	219 (59.8)	117 (32.0)	102 (27.9)
H. pylori infection				0.470
No	145 (89.0)	63 (38.7)	82 (50.3)
Yes	18 (11.0)	10 (6.1)	8 (4.9)
OS event				0.022
Alive	228 (60.8)	125 (33.3)	103 (27.5)
Dead	147 (39.2)	62 (16.5)	85 (22.7)
Age, mean ± SD		65.39 ± 10.80	66.28 ± 10.51	0.423

The bold means statistical significance. MIB1: Mind bomb 1; OS: Overall survival; H. pylori: Helicobacter pylori.