Synergistic effect of cell differential agent-II and arsenic trioxide on induction of cell cycle arrest and apoptosis in hepatoma cells

Table 1 Survival rate of hepatoma cell lines HepG2 treated with drugs (x±s)%

Groups	cB,B/(µmol·L-1)a or ρB,C/(g·L-1)b
	1.0	2.0	3.0	4.0	5.0c
A (Comtrols)	100	100	100	100	100
B (As2O3,cB)d	80.06 ± 3.27	70.58 ± 5.42	67.82 ± 3.43	59.33 ± 7.33	49.12 ± 4.25
C (CDA-II, ρB)e	92.41 ± 4.25	81.22 ± 7.34	70.23 ± 2.32	68.22 ± 4.56	67.12 ± 9.23
D (B + C1.0)f	50.67 ± 3.56	47.88 ± 6.42	47.34 ± 4.25	45.54 ± 8.22	41.55 ± 3.75

^ac_B,B/(µmol·L^-1) is for group B (As₂O_3,c_B); ρ_B,C/(g·L^-1) is for group C (CDA-II, ρ_B);

^bgroup D (B + C_1.0) refers to every each group B (As₂O₃, c_B,B) plus ρ_{B, C} = 1.0 g·L^-1;

^cConcentration grads effect: F = 32.270, sig. = 0.000, P < 0.05;

^dMain effect for group B (As₂O_3,c_B): F = 22.856, sig. = 0.000, P < 0.05;

^eMain effect for group C (CDA-II, ρ_B): F = 0.831, sig. = 0.059, P > 0.05;

^fInteraction effect for group D (B + C_1.0): F = 27.178, sig. = 0.000, P < 0.05