Discovery of unique African Helicobacter pylori CagA-multimerization motif in the Dominican Republic

doi:10.3748/wjg.v26.i45.7118

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Dec 7, 2020; 26(45): 7118-7130
Published online Dec 7, 2020. doi: 10.3748/wjg.v26.i45.7118

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Figure 1 Variation in the CagA (Glu-Pro-Ile-Tyr-Ala)-A region from the Dominican Republic strains. A: CagA Glu-Pro-Ile-Tyr-Ala (EPIYA)-A region in 52 strains without containing “GKDKGPE” motif (excluding two AC-type strains); B: CagA EPIYA-A region in 30 strains containing “GKDKGPE” motif. The reference sequences[19] are shown at the bottom of the figure (green); C: Most frequent Western-type CagA EPIYA-A region; D: Most frequent East Asian-type CagA EPIYA-A region.

Citation: Ono T, Cruz M, Nagashima H, Subsomwong P, Akada J, Matsumoto T, Uchida T, Suzuki R, Hosking C, Jiménez Abreu JA, Yamaoka Y. Discovery of unique African Helicobacter pylori CagA-multimerization motif in the Dominican Republic. World J Gastroenterol 2020; 26(45): 7118-7130
URL: https://www.wjgnet.com/1007-9327/full/v26/i45/7118.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i45.7118