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Copyright ©The Author(s) 2019.
World J Gastroenterol. Sep 28, 2019; 25(36): 5423-5433
Published online Sep 28, 2019. doi: 10.3748/wjg.v25.i36.5423
Table 2 Summary of the major causes of infertility in the general population and a few specific situations related to inflammatory bowel disease
WomenMen
General risk factors:
Age: High fertility rate around 25 yr, then gradually reduce and more quickly after 35 yrGeneral risk factors:
High age
Tobacco
Addiction and lead poisoning
Tobacco
Ovulation disorders: Obesity or thinness/hyperprolactinaemia/polycystic ovary syndrome/hypothalamic amenorrhoea, etcOligoasthenoteratospermia (the most common cause for male infertility)
Sulfasalazine
Azoospermia (hypogonadism induced or blockages)
Diseases with chronic inflammation
Sulfasalazine
Mechanical obstruction:
Tubal obstruction (frequent cause after a salpingitis or endometriosis)
Ileal pouch-anal anastomosis by laparotomy, Crohn’s disease with severe pelvic inflammation with or without prior surgery
Uterine malformation, uterine synechiae or endometriosis
Cervical stenosis