Autoantibodies: Potential clinical applications in early detection of esophageal squamous cell carcinoma and esophagogastric junction adenocarcinoma

Table 1 A brief summary of the biological significance of some common tumor-associated autoantibodies

Representative tumor-associated autoantigens	Authors, year	Tumor type	Biological significance
p53	Chapman et al[11], 2012	Lung	Early detection
	Takeda et al[14], 2001	Colorectal	Increased recurrence
	Anderson et al[15], 2010	Ovarian	Increased survival
NY-ESO-1	Shan et al[16], 2013	Lung	Early detection
	Fosså et al[17], 2004	Prostate	Decreased survival
	Elke et al[18], 1999	Melanoma	Therapeutic monitoring
MUC1	Pedersen et al[19], 2014	Ovarian	Early detection
	Kurtenkov et al[20], 2007	Gastric	Increased survival
Hu	Chapman et al[11], 2011	Lung	Early detection
	Graus et al[21], 1997	Lung	Therapeutic monitoring and increased survival

MUC1: Mucin-1.