Autophagy activation by Jiang Zhi Granule protects against metabolic stress-induced hepatocyte injury

Figure 3 Effects of Jiang Zhi Granule on autophagic flux in palmitate-treated cells. A: HepG2 cells stably expressing mCherry-p62 were pretreated with 0.4 mmol/L PA and rapamycin (2 μmol/L) or JZG (100 μg/mL) for 24 h and 48 h, and then analyzed by fluorescence microscopy; B: HepG2 cells were treated with 0.4 mmol/L PA and rapamycin (2 μmol/L) or JZG (100 μg/mL) for 48 h, and then analyzed by fluorescence microscopy. JZG: Jiang Zhi Granule; PA: Palmitate.