Predictors of post-treatment stenosis in cervical esophageal cancer undergoing high-dose radiotherapy

Table 3 Factors influencing occurrence of post-radiotherapy stenosis n (%)

Characteristics	No. of Patients	Stenosis		P value
		No	Yes	Univariate	Multivariate
Age
≤ 65	30	24 (80)	6 (20)	0.236
> 65	32	22 (69)	10 (31)
T stage
T1/2	20	20 (100)	0	0.001	0.998
T3/4	42	26 (62)	16 (38)
Involved circumference
< 100%	40	37 (93)	3 (7)	< 0.0001	0.003
100%	22	9 (41)	13 (59)
Total length
< 5.0	28	22 (79)	6 (921)	0.338
≥ 5.0	34	24 (71)	10 (29)
Stenosis at diagnosis
No	45	37 (82)	8 (18)	0.024	0.995
Yes	17	9 (53)	8 (47)
Dysphagia at diagnosis
≤ 1 mo	36	30 (83)	6 (17)	0.051
> 1 mo	26	16 (62)	10 (38)
RT dose
≥ 60 Gy	37	27 (73)	10 (27)	0.515
< 60 Gy	25	19 (76)	6 (24)
Endoscopic response
CR	39	33 (85)	6 (15)	0.017	0.740
< CR	23	13 (56)	10 (44)

RT: Radiotherapy; CR: Complete response.