Colonic lesion characterization in inflammatory bowel disease: A systematic review and meta-analysis

Table 2 quality assessment of diagnostic accuracy studies 2 for each study

	Cassinotti et al[22] 2016	Efthymiou et al[21]2013	Van den broek et al[23]2011	Cassinottiet al[24]2015	Cassinottiet al[25]2015	Carballel et al[26]2016	Buchner et al[27]2016	Wanders et al[20]2016	Munoz et al[28]2016	Wanders et al[29]2015	Hlavaty et al[18]2011	Dlugosz et al[30]2016	Freireet al[31]2014	Rispoet al[32]2012	Shahidet al[33]2011	Van den broek et al[19] 2011	Keisslichet al[34]2007	Nishiyamaet al[35]2016	Van den Broek et al[36]2008	Matsumotoet al[37]2007	Keisslich et al[38]2003	Bisschopset al[39]2013
DOMAIN 1
Patient selection
Risk of bias
Could selection of patients introduced bias?	L	L	L	L	L	L	U	L	L	H	U	L	L	L	H	H	L	H	L	L	L	H
Concerns regarding applicability
Concern included patients don’t match review question?	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L
DOMAIN 2
Index test
Risk of bias
Conduct or interpretation of index test introduced bias?	L	L	L	L	L	L	L	L	U	H	H	H	L	L	H	H	L	H	L	L	L	H
Concerns regarding applicability
Concern index test, its conduct or interpretation differs from review question?	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L
DOMAIN 3
Reference standard
Risk of bias
Could reference standard, conduct or interpretation have introduced bias?	U	U	L	U	U	U	U	L	U	U	L	L	L	L	U	L	L	U	L	L	L	U
Concerns regarding applicability
Concern target condition as defined by reference standard not match review question?	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L	L
DOMAIN 4
Flow and timing
Risk of bias
Could patient flow introduced bias?	U	L	H	U	U	L	U	L	U	H	H	U	L	L	H	H	L	H	L	L	L	H

L: Low risk; H: High risk; U: Unclear.